Explore TRPM7 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T11906
|
| Target Name |
TRPM7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
54822
|
| Gene ID |
101095177 (Felis catus), 102149157 (Equus caballus), 478300 (Canis lupus familiaris), 514642 (Bos taurus)
54822 (Homo sapiens), 58800 (Mus musculus), 679906 (Rattus norvegicus), 716755 (Macaca mulatta)
|
| Target Alternative Names |
2310022G15Rik,4833414K03Rik,5033407O22Rik,ALSPDC,CHAK,CHAK1,Chak,Channel-kinase 1,LTRPC7,LTrpC-7,LTrpC7),Long transient receptor potential channel 7 (LTrpC-7,Ltpr7,Ltrpc7,TRP-PLIK,TRPM7,TRPPLIK,Transient receptor potential cation channel subfamily M member 7,Trp-plik,Trpm7
|
| Uniprot Accession |
Q96QT4,Q923J1,Q925B3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Cellular senescence, NOD-like receptor signaling pathway, Mineral absorption
|
| Gene Ensembl |
ENSECAG00000017780, ENSCAFG00845024080, ENSBTAG00000031165, ENSG00000092439, ENSMUSG00000027365, ENSMMUG00000008575
|
| Target Classification |
Kinase
|
TRPM7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54822 | Pre-made Human TRPM7/CHAK/CHAK1 siRNA oligo Duplex | 54822 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo679906 | Pre-made Rat Trpm7/Chak/Ltrpc7 siRNA oligo Duplex | 679906 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58800 | Pre-made Mouse Trpm7/CHAK/CHAK1 siRNA oligo Duplex | 58800 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716755 | Pre-made Cynomolgus/Rhesus macaque TRPM7 siRNA oligo Duplex | 716755 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095177 | Pre-made Cat/Feline TRPM7 siRNA oligo Duplex | 101095177 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478300 | Pre-made Dog/Canine TRPM7 siRNA oligo Duplex | 478300 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514642 | Pre-made Bovines/Cattle TRPM7 siRNA oligo Duplex | 514642 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149157 | Pre-made Equine/Horse TRPM7 siRNA oligo Duplex | 102149157 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TRPM7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11906-Ab | Human | Anti-Human TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T11906-Ab | Rat | Anti-Rat TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T11906-Ab | Mouse | Anti-Mouse TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T11906-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T11906-Ab | Cat/Feline | Anti-Cat/Feline TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T11906-Ab | Dog/Canine | Anti-Dog/Canine TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T11906-Ab | Bovines/Cattle | Anti-Bovines/Cattle TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T11906-Ab | Equine/Horse | Anti-Equine/Horse TRPM7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TRPM7 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11906-Ag | Human | Human TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T11906-Ag | Rat | Rat TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T11906-Ag | Mouse | Mouse TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T11906-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T11906-Ag | Cat/Feline | Cat/Feline TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T11906-Ag | Dog/Canine | Dog/Canine TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T11906-Ag | Bovines/Cattle | Bovines/Cattle TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T11906-Ag | Equine/Horse | Equine/Horse TRPM7 VLP (virus-like particle) | HEK293 | Products Developing |
