Explore DDR2/CD167b gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T11764
|
| Target Name |
DDR2/CD167b
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4921
|
| Gene ID |
100058300 (Equus caballus), 101085267 (Felis catus), 18214 (Mus musculus), 478987 (Canis lupus familiaris) 4921 (Homo sapiens), 533523 (Bos taurus), 685781 (Rattus norvegicus), 720124 (Macaca mulatta)
|
| Target Alternative Names |
CD167 antigen-like family member B,CD167b,DDR2,Ddr2,Discoidin domain receptor 2,Discoidin domain-containing receptor 2,Discoidin domain-containing receptor tyrosine kinase 2,MIG20a,NTRKR3,Neurotrophic tyrosine kinase,Ntrkr3,Receptor protein-tyrosine kinase TKT,TKT,TYRO10,Tyro10,Tyrosine-protein kinase TYRO10,WRCN,receptor-related 3,tyro10
|
| Uniprot Accession |
Q62371,Q16832
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Non-Small Cell Lung Cancer
|
| Gene Ensembl |
ENSECAG00000010726, ENSMUSG00000026674, ENSCAFG00845026475, ENSG00000162733, ENSBTAG00000004885, ENSMMUG00000009330
|
| Target Classification |
Kinase
|
Pre-made viral vector of DDR2/CD167b cDNA Clones/ORF Plasmid
DDR2/CD167b siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4921 | Pre-made Human DDR2/TKT/WRCN siRNA oligo Duplex | 4921 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo685781 | Pre-made Rat Ddr2/Tyro10 siRNA oligo Duplex | 685781 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18214 | Pre-made Mouse Ddr2/Ntrkr3/tyro10 siRNA oligo Duplex | 18214 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720124 | Pre-made Cynomolgus/Rhesus macaque DDR2 siRNA oligo Duplex | 720124 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085267 | Pre-made Cat/Feline DDR2 siRNA oligo Duplex | 101085267 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478987 | Pre-made Dog/Canine DDR2 siRNA oligo Duplex | 478987 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533523 | Pre-made Bovines/Cattle DDR2 siRNA oligo Duplex | 533523 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058300 | Pre-made Equine/Horse DDR2 siRNA oligo Duplex | 100058300 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DDR2/CD167b antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11764-Ab | Human | Anti-Human DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T11764-Ab | Rat | Anti-Rat DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T11764-Ab | Mouse | Anti-Mouse DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T11764-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T11764-Ab | Cat/Feline | Anti-Cat/Feline DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T11764-Ab | Dog/Canine | Anti-Dog/Canine DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T11764-Ab | Bovines/Cattle | Anti-Bovines/Cattle DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T11764-Ab | Equine/Horse | Anti-Equine/Horse DDR2/CD167b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DDR2/CD167b VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11764-Ag | Human | Human DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T11764-Ag | Rat | Rat DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T11764-Ag | Mouse | Mouse DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T11764-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T11764-Ag | Cat/Feline | Cat/Feline DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T11764-Ag | Dog/Canine | Dog/Canine DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T11764-Ag | Bovines/Cattle | Bovines/Cattle DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T11764-Ag | Equine/Horse | Equine/Horse DDR2/CD167b VLP (virus-like particle) | HEK293 | Products Developing |