SLC7A11/xCT Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SLC7A11/xCT gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]

Target ID GM-T11615
Target Name SLC7A11/xCT
Gene Group ldentifer
（Target Gene ID in Homo species) 		23657
Gene ID 100063433 (Equus caballus), 101099374 (Felis catus), 23657 (Homo sapiens), 26570 (Mus musculus)
310392 (Rattus norvegicus), 483821 (Canis lupus familiaris), 524078 (Bos taurus), 696516 (Macaca mulatta)
Target Alternative Names 9930009M05Rik,Amino acid transport system xc-,CCBR1,Calcium channel blocker resistance protein CCBR1,Cystine/glutamate transporter,SLC7A11,Slc7a11,Solute carrier family 7 member 11,sut,xCT
Uniprot Accession Q9UPY5,Q9WTR6
Protein Sub-location Transmembrane Protein
Disease from KEGG Ferroptosis
Gene Ensembl ENSECAG00000022696, ENSG00000151012, ENSMUSG00000027737, ENSCAFG00845022942, ENSBTAG00000034075, ENSMMUG00000020317


Pre-made viral vector of SLC7A11/xCT cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002698Human SLC7A11/CCBR1/xCT Lentivirus plasmidNM_01433123657HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000895Human SLC7A11/CCBR1/xCT Mammalian (Non-Viral Vector) plasmidNM_014331.323657HumanMammalian (Non-Viral Vector) plasmidEGFPNullEF1Detail
vGMAD000772Human SLC7A11/CCBR1/xCT Adenovirus particleNM_014331.423657HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
vGMLV002421Human SLC7A11/CCBR1/xCT Lentivirus particleNM_014331.423657HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMLV002270Human SLC7A11/CCBR1/xCT Lentivirus particleNM_014331.423657HumanLentivirus particleNullNullCMVDetail
vGMLV000645Human SLC7A11/CCBR1/xCT Lentivirus particleNM_014331.323657HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002698Human SLC7A11/CCBR1/xCT Lentivirus particleNM_01433123657HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000645Human SLC7A11/CCBR1/xCT Lentivirus plasmidNM_014331.323657HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000954Human SLC7A11/CCBR1/xCT Mammalian (Non-Viral Vector) plasmidNM_01433123657HumanMammalian (Non-Viral Vector) plasmidEGFPMYC (C-Terminal)EF1Detail
pGMPC000851Human SLC7A11/CCBR1/xCT Mammalian (Non-Viral Vector) plasmidNM_014331.423657HumanMammalian (Non-Viral Vector) plasmidEGFPMYC (C-Terminal)EF1Detail
pGMAD000772Human SLC7A11/CCBR1/xCT Adenovirus plasmidNM_014331.423657HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMLV002421Human SLC7A11/CCBR1/xCT Lentivirus plasmidNM_014331.423657HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMLV002270Human SLC7A11/CCBR1/xCT Lentivirus plasmidNM_014331.423657HumanLentivirus plasmidNullNullCMVDetail
pGMLPm004468Mouse Slc7a11/9930009M05Rik/AI451155 Lentivirus plasmidNM_01199026570MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC001218Mouse Slc7a11/9930009M05Rik/AI451155 Mammalian (Non-Viral Vector) plasmidNM_01199026570MouseMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
pGMAAV000720Mouse Slc7a11/9930009M05Rik/AI451155 Adeno-associate virus(AAV) plasmidNM_01199026570MouseAdeno-associate virus(AAV) plasmidZsGreenNullCMVDetail
pGMAD001620Mouse Slc7a11/9930009M05Rik/sut Adenovirus plasmidNM_011990.226570MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAD001620Mouse Slc7a11/9930009M05Rik/sut Adenovirus particleNM_011990.226570MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
vGMAAV000720Mouse Slc7a11/9930009M05Rik/AI451155 Adeno-associate virus(AAV) particleNM_01199026570MouseAdeno-associate virus(AAV) particleZsGreenNullCMVDetail
vGMLPm004468Mouse Slc7a11/9930009M05Rik/AI451155 Lentivirus particleNM_01199026570MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


SLC7A11/xCT siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo23657Pre-made Human SLC7A11/xCT/CCBR1 siRNA oligo Duplex23657HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo310392Pre-made Rat Slc7a11 siRNA oligo Duplex310392RatIn-vitro grade; in-vivo gradeDetail
pGMoligo26570Pre-made Mouse Slc7a11/sut/xCT siRNA oligo Duplex26570MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo696516Pre-made Cynomolgus/Rhesus macaque SLC7A11 siRNA oligo Duplex696516Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101099374Pre-made Cat/Feline SLC7A11 siRNA oligo Duplex101099374Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo483821Pre-made Dog/Canine SLC7A11/xCT siRNA oligo Duplex483821Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo524078Pre-made Bovines/Cattle SLC7A11 siRNA oligo Duplex524078Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100063433Pre-made Equine/Horse SLC7A11 siRNA oligo Duplex100063433Equine/HorseIn-vitro grade; in-vivo gradeDetail


SLC7A11/xCT antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T11615-AbHumanAnti-Human SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-rg-T11615-AbRatAnti-Rat SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-mg-T11615-AbMouseAnti-Mouse SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cynog-T11615-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-felg-T11615-AbCat/FelineAnti-Cat/Feline SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cang-T11615-AbDog/CanineAnti-Dog/Canine SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-bovg-T11615-AbBovines/CattleAnti-Bovines/Cattle SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-equg-T11615-AbEquine/HorseAnti-Equine/Horse SLC7A11/xCT monoclonal antibodymabFACS/Biofunctional AntibodyDetail


SLC7A11/xCT VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T11615-AgHumanHuman SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T11615-AgRatRat SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T11615-AgMouseMouse SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T11615-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T11615-AgCat/FelineCat/Feline SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T11615-AgDog/CanineDog/Canine SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T11615-AgBovines/CattleBovines/Cattle SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T11615-AgEquine/HorseEquine/Horse SLC7A11/xCT VLP (virus-like particle)HEK293Products Developing