Explore SLC7A11/xCT gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
| Target ID |
GM-T11615
|
| Target Name |
SLC7A11/xCT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23657
|
| Gene ID |
100063433 (Equus caballus), 101099374 (Felis catus), 23657 (Homo sapiens), 26570 (Mus musculus)
310392 (Rattus norvegicus), 483821 (Canis lupus familiaris), 524078 (Bos taurus), 696516 (Macaca mulatta)
|
| Target Alternative Names |
SLC7A11,Slc7a11,xCT,CCBR1,sut,9930009M05Rik
|
| Uniprot Accession |
Q9UPY5,Q9WTR6
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Ferroptosis
|
| Gene Ensembl |
ENSECAG00000022696, ENSG00000151012, ENSMUSG00000027737, ENSCAFG00845022942, ENSBTAG00000034075, ENSMMUG00000020317
|
| Target Classification |
|
Pre-made viral vector of SLC7A11/xCT cDNA Clones/ORF Plasmid
SLC7A11/xCT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23657 | Pre-made Human SLC7A11/xCT/CCBR1 siRNA oligo Duplex | 23657 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo310392 | Pre-made Rat Slc7a11 siRNA oligo Duplex | 310392 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26570 | Pre-made Mouse Slc7a11/sut/xCT siRNA oligo Duplex | 26570 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696516 | Pre-made Cynomolgus/Rhesus macaque SLC7A11 siRNA oligo Duplex | 696516 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099374 | Pre-made Cat/Feline SLC7A11 siRNA oligo Duplex | 101099374 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483821 | Pre-made Dog/Canine SLC7A11/xCT siRNA oligo Duplex | 483821 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524078 | Pre-made Bovines/Cattle SLC7A11 siRNA oligo Duplex | 524078 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063433 | Pre-made Equine/Horse SLC7A11 siRNA oligo Duplex | 100063433 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SLC7A11/xCT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11615-Ab | Human | Anti-Human SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-T11615-Ab | Rat | Anti-Rat SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-T11615-Ab | Mouse | Anti-Mouse SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-T11615-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-T11615-Ab | Cat/Feline | Anti-Cat/Feline SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-T11615-Ab | Dog/Canine | Anti-Dog/Canine SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-T11615-Ab | Bovines/Cattle | Anti-Bovines/Cattle SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-T11615-Ab | Equine/Horse | Anti-Equine/Horse SLC7A11/xCT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SLC7A11/xCT VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11615-Ag | Human | Human SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T11615-Ag | Rat | Rat SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T11615-Ag | Mouse | Mouse SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T11615-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T11615-Ag | Cat/Feline | Cat/Feline SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T11615-Ag | Dog/Canine | Dog/Canine SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T11615-Ag | Bovines/Cattle | Bovines/Cattle SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T11615-Ag | Equine/Horse | Equine/Horse SLC7A11/xCT VLP (virus-like particle) | HEK293 | Products Developing |
