Explore TLR9/CD289 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T11451
|
| Target Name |
TLR9/CD289
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
54106
|
| Gene ID |
100009693 (Equus caballus), 282602 (Bos taurus), 338457 (Rattus norvegicus), 493839 (Felis catus)
54106 (Homo sapiens), 574395 (Macaca mulatta), 81897 (Mus musculus)
|
| Target Alternative Names |
CD289,TLR9,Tlr9,Toll-like receptor 9
|
| Uniprot Accession |
Q2EEY0,Q5I2M5,Q5I2M7,Q9NR96,Q9EQU3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Toll-like receptor signaling pathway, Chagas disease, African trypanosomiasis, Malaria, Tuberculosis, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer
|
| Gene Ensembl |
ENSBTAG00000018198, ENSG00000239732, ENSMMUG00000012263,ENSMMUG00000047685, ENSMUSG00000045322
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of TLR9/CD289 cDNA Clones/ORF Plasmid
TLR9/CD289 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54106 | Pre-made Human TLR9/CD289 siRNA oligo Duplex | 54106 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo338457 | Pre-made Rat Tlr9 siRNA oligo Duplex | 338457 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81897 | Pre-made Mouse Tlr9 siRNA oligo Duplex | 81897 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574395 | Pre-made Cynomolgus/Rhesus macaque TLR9 siRNA oligo Duplex | 574395 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493839 | Pre-made Cat/Feline TLR9 siRNA oligo Duplex | 493839 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282602 | Pre-made Bovines/Cattle TLR9 siRNA oligo Duplex | 282602 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009693 | Pre-made Equine/Horse TLR9 siRNA oligo Duplex | 100009693 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TLR9/CD289 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11451-Ab | Human | Anti-Human TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T11451-Ab | Rat | Anti-Rat TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T11451-Ab | Mouse | Anti-Mouse TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T11451-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T11451-Ab | Cat/Feline | Anti-Cat/Feline TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T11451-Ab | Bovines/Cattle | Anti-Bovines/Cattle TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T11451-Ab | Equine/Horse | Anti-Equine/Horse TLR9/CD289 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TLR9/CD289 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11451-Ag | Human | Human TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T11451-Ag | Rat | Rat TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T11451-Ag | Mouse | Mouse TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T11451-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T11451-Ag | Cat/Feline | Cat/Feline TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T11451-Ag | Bovines/Cattle | Bovines/Cattle TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T11451-Ag | Equine/Horse | Equine/Horse TLR9/CD289 VLP (virus-like particle) | HEK293 | Products Developing |
