ADRA2A Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore ADRA2A gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. The alpha-2-adrenergic receptors are a type of adrenergic receptors (for adrenaline or epinephrine), which inhibit adenylate cyclase. These receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. They are involved in regulating the release of neurotransmitter molecules from sympathetic nerves and from adrenergic neurons in the central nervous system. The sympathetic nervous system regulates cardiovascular function by activating adrenergic receptors in the heart, blood vessels and kidney. Studies in mouse revealed that both the alpha2A and alpha2C receptor subtypes were required for presynaptic transmitter release from the sympathetic nervous system in the heart and from central noradrenergic neurons. The alpha-2-adrenergic receptors are also involved in catecholamine signaling by extracellular regulated protein kinase 1 and 2 (ERK1/2) pathways. A clear association between the alpha-2-adrenergic receptor and disease has not been yet established. [provided by RefSeq, Sep 2019]

Target ID GM-T11448
Target Name ADRA2A
Gene Group ldentifer
(Target Gene ID in Homo species)
150
Gene ID 100147119 (Equus caballus), 11551 (Mus musculus), 150 (Homo sapiens), 25083 (Rattus norvegicus)
282135 (Bos taurus), 486888 (Canis lupus familiaris), 664736 (Felis catus), 695684 (Macaca mulatta)
Target Alternative Names ADRA2A,Adra2a,Adra-2,Adra-2a,alpha2A,alpha2-C10,alpha2A-AR,alpha(2A)AR,ADRA2,ADRAR,FPLD8,ZNF32,ADRA2R,ALPHA2AAR,RG20,CA2-47,RATRG20
Uniprot Accession Q01338,P08913,P22909,Q28838
Uniprot Entry Name
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease
Disease from KEGG cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction
Gene Ensembl ENSECAG00000059760, ENSMUSG00000033717, ENSG00000150594, ENSBTAG00000039292, ENSCAFG00845029289, ENSMMUG00000041307
Target Classification GPCR


Pre-made viral vector of ADRA2A cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP003730Human ADRA2A/ADRA2/ADRA2R Lentivirus plasmidNM_000681150HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP003730Human ADRA2A/ADRA2/ADRA2R Lentivirus particleNM_000681150HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


ADRA2A siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo150Pre-made Human ADRA2A/ADRA2/ADRAR siRNA oligo Duplex150HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25083Pre-made Rat Adra2a/RG20/CA2-47 siRNA oligo Duplex25083RatIn-vitro grade; in-vivo gradeDetail
pGMoligo11551Pre-made Mouse Adra2a/Adra-2/Adra-2a siRNA oligo Duplex11551MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo695684Pre-made Cynomolgus/Rhesus macaque ADRA2A siRNA oligo Duplex695684Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo664736Pre-made Cat/Feline ADRA2A siRNA oligo Duplex664736Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo486888Pre-made Dog/Canine ADRA2A siRNA oligo Duplex486888Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo282135Pre-made Bovines/Cattle ADRA2A siRNA oligo Duplex282135Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100147119Pre-made Equine/Horse ADRA2A siRNA oligo Duplex100147119Equine/HorseIn-vitro grade; in-vivo gradeDetail


ADRA2A antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T11448-AbHumanAnti-Human ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T11448-AbRatAnti-Rat ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T11448-AbMouseAnti-Mouse ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T11448-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T11448-AbCat/FelineAnti-Cat/Feline ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T11448-AbDog/CanineAnti-Dog/Canine ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T11448-AbBovines/CattleAnti-Bovines/Cattle ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T11448-AbEquine/HorseAnti-Equine/Horse ADRA2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


ADRA2A VLP (virus-like particle)

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T11448-AgHumanHuman ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T11448-AgRatRat ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T11448-AgMouseMouse ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T11448-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T11448-AgCat/FelineCat/Feline ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T11448-AgDog/CanineDog/Canine ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T11448-AgBovines/CattleBovines/Cattle ADRA2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T11448-AgEquine/HorseEquine/Horse ADRA2A VLP (virus-like particle)HEK293Products Developing