Explore MRP1/ABCC1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
| Target ID |
GM-T11288
|
| Target Name |
MRP1/ABCC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4363
|
| Gene ID |
101101279 (Felis catus), 17250 (Mus musculus), 24565 (Rattus norvegicus), 281588 (Bos taurus)
403453 (Canis lupus familiaris), 4363 (Homo sapiens), 717857 (Macaca mulatta), 791240 (Equus caballus)
|
| Target Alternative Names |
ABC29,ABCC,ABCC1,ATP-binding cassette sub-family C member 1,Abcc1,Abcc1a,Abcc1b,Avcc1a,DFNA77,GS-X,Glutathione-S-conjugate-translocating ATPase ABCC1,Leukotriene C(4) transporter (LTC4 transporter),MRP,MRP1,Mdrap,Mrp,Mrp1,Multidrug resistance-associated protein 1
|
| Uniprot Accession |
O35379,Q8CG09,Q8HXQ5,Q6UR05,P33527
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Antifolate resistance, ABC transporters, Sphingolipid signaling pathway, Vitamin digestion and absorption
|
| Gene Ensembl |
ENSMUSG00000023088, ENSBTAG00000021090, ENSCAFG00845007668, ENSG00000103222, ENSMMUG00000005914, ENSECAG00000006784
|
| Target Classification |
Tumor-associated antigen (TAA)
|
MRP1/ABCC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4363 | Pre-made Human ABCC1/MRP/ABCC siRNA oligo Duplex | 4363 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24565 | Pre-made Rat Abcc1/Mrp/Mrp1 siRNA oligo Duplex | 24565 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17250 | Pre-made Mouse Abcc1/MRP/Mrp1 siRNA oligo Duplex | 17250 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717857 | Pre-made Cynomolgus/Rhesus macaque ABCC1 siRNA oligo Duplex | 717857 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101279 | Pre-made Cat/Feline ABCC1 siRNA oligo Duplex | 101101279 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403453 | Pre-made Dog/Canine ABCC1/MRP1 siRNA oligo Duplex | 403453 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281588 | Pre-made Bovines/Cattle ABCC1 siRNA oligo Duplex | 281588 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo791240 | Pre-made Equine/Horse ABCC1 siRNA oligo Duplex | 791240 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MRP1/ABCC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11288-Ab | Human | Anti-Human MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T11288-Ab | Rat | Anti-Rat MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T11288-Ab | Mouse | Anti-Mouse MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T11288-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T11288-Ab | Cat/Feline | Anti-Cat/Feline MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T11288-Ab | Dog/Canine | Anti-Dog/Canine MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T11288-Ab | Bovines/Cattle | Anti-Bovines/Cattle MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T11288-Ab | Equine/Horse | Anti-Equine/Horse MRP1/ABCC1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MRP1/ABCC1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11288-Ag | Human | Human MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T11288-Ag | Rat | Rat MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T11288-Ag | Mouse | Mouse MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T11288-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T11288-Ag | Cat/Feline | Cat/Feline MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T11288-Ag | Dog/Canine | Dog/Canine MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T11288-Ag | Bovines/Cattle | Bovines/Cattle MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T11288-Ag | Equine/Horse | Equine/Horse MRP1/ABCC1 VLP (virus-like particle) | HEK293 | Products Developing |
