Explore HSP60/HSPD1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]
| Target ID |
GM-T11283
|
| Target Name |
HSP60/HSPD1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3329
|
| Gene ID |
100055147 (Equus caballus), 101088683 (Felis catus), 15510 (Mus musculus), 3329 (Homo sapiens) 478854 (Canis lupus familiaris), 511913 (Bos taurus), 63868 (Rattus norvegicus), 698024 (Macaca mulatta)
|
| Target Alternative Names |
60 kDa chaperonin,60 kDa heat shock protein,60kDa,CPN60,Chaperonin 60 (CPN60),GROEL,HLD4,HSP-60,HSP-65,HSP60,HSP65,HSPD1,Heat shock protein 60 (HSP-60,Heat shock protein family D member 1,Hsp60,Hsp60),Hspd1,Hspd1-30p,HuCHA60,Mitochondrial matrix protein P1,P60 lymphocyte protein,SPG13,mitochondrial
|
| Uniprot Accession |
P63038,P10809,P49818,P63039
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Malignant neoplasm of bladder, Liver cell carcinoma
|
| Disease from KEGG |
Type I diabetes mellitus, Legionellosis, Tuberculosis, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000008968, ENSMUSG00000025980, ENSG00000144381, ENSCAFG00845027075, ENSBTAG00000012586, ENSMMUG00000010489
|
Pre-made viral vector of HSP60/HSPD1 cDNA Clones/ORF Plasmid
HSP60/HSPD1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3329 | Pre-made Human HSPD1/HLD4/CPN60 siRNA oligo Duplex | 3329 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo63868 | Pre-made Rat Hspd1/Hsp60/Hspd1-30p siRNA oligo Duplex | 63868 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15510 | Pre-made Mouse Hspd1/60kDa/CPN60 siRNA oligo Duplex | 15510 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698024 | Pre-made Cynomolgus/Rhesus macaque HSPD1/Hsp60 siRNA oligo Duplex | 698024 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088683 | Pre-made Cat/Feline HSPD1 siRNA oligo Duplex | 101088683 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478854 | Pre-made Dog/Canine HSPD1/CPN60/Hsp60 siRNA oligo Duplex | 478854 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511913 | Pre-made Bovines/Cattle HSPD1/HSP60 siRNA oligo Duplex | 511913 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055147 | Pre-made Equine/Horse HSPD1 siRNA oligo Duplex | 100055147 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HSP60/HSPD1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T11283-Ab | Human | Anti-Human HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T11283-Ab | Rat | Anti-Rat HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T11283-Ab | Mouse | Anti-Mouse HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T11283-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T11283-Ab | Cat/Feline | Anti-Cat/Feline HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T11283-Ab | Dog/Canine | Anti-Dog/Canine HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T11283-Ab | Bovines/Cattle | Anti-Bovines/Cattle HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T11283-Ab | Equine/Horse | Anti-Equine/Horse HSP60/HSPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HSP60/HSPD1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T11283-Ag | Human | Human HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T11283-Ag | Rat | Rat HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T11283-Ag | Mouse | Mouse HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T11283-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T11283-Ag | Cat/Feline | Cat/Feline HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T11283-Ag | Dog/Canine | Dog/Canine HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T11283-Ag | Bovines/Cattle | Bovines/Cattle HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T11283-Ag | Equine/Horse | Equine/Horse HSP60/HSPD1 VLP (virus-like particle) | HEK293 | Products Developing |