Explore CD62P/P-selectin/SELP gene products and cross-species
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Target
sublocation: Transmembrane Protein.
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T10965
|
| Target Name |
CD62P/P-selectin/SELP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6403
|
| Gene ID |
100009695 (Equus caballus), 101083565 (Felis catus), 20344 (Mus musculus), 25651 (Rattus norvegicus) 281486 (Bos taurus), 403994 (Canis lupus familiaris), 6403 (Homo sapiens), 701277 (Macaca mulatta)
|
| Target Alternative Names |
CD62,CD62 antigen-like family member P,CD62P,GMP-140,GMP140,GRMP,Granule membrane protein 140 (GMP-140),Grmp,LECAM3,Leukocyte-endothelial cell adhesion molecule 3 (LECAM3),P-selectin,PADGEM,PSEL,PSELECT,Platelet activation dependent granule-external membrane protein (PADGEM),SELP,Selp
|
| Uniprot Accession |
Q01102,P98106,P42201,P16109
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
Hodgkin's lymphoma, Sepsis
|
| Disease from KEGG |
Cell adhesion molecules, Malaria, Staphylococcus aureus infection, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000010918, ENSMUSG00000026580, ENSBTAG00000020755, ENSCAFG00845002229, ENSG00000174175, ENSMMUG00000013044
|
Pre-made viral vector of CD62P/P-selectin/SELP cDNA Clones/ORF Plasmid
CD62P/P-selectin/SELP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6403 | Pre-made Human SELP/CD62/GRMP siRNA oligo Duplex | 6403 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25651 | Pre-made Rat Selp/PSELECT siRNA oligo Duplex | 25651 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20344 | Pre-made Mouse Selp/Grmp/CD62P siRNA oligo Duplex | 20344 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701277 | Pre-made Cynomolgus/Rhesus macaque SELP siRNA oligo Duplex | 701277 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083565 | Pre-made Cat/Feline SELP siRNA oligo Duplex | 101083565 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403994 | Pre-made Dog/Canine SELP/GMP140 siRNA oligo Duplex | 403994 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281486 | Pre-made Bovines/Cattle SELP siRNA oligo Duplex | 281486 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009695 | Pre-made Equine/Horse SELP/CD62P siRNA oligo Duplex | 100009695 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD62P/P-selectin/SELP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T10965-Ab | Human | Anti-Human CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T10965-Ab | Rat | Anti-Rat CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T10965-Ab | Mouse | Anti-Mouse CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T10965-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T10965-Ab | Cat/Feline | Anti-Cat/Feline CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T10965-Ab | Dog/Canine | Anti-Dog/Canine CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T10965-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T10965-Ab | Equine/Horse | Anti-Equine/Horse CD62P/P-selectin/SELP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD62P/P-selectin/SELP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T10965-Ag | Human | Human CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T10965-Ag | Rat | Rat CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T10965-Ag | Mouse | Mouse CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T10965-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T10965-Ag | Cat/Feline | Cat/Feline CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T10965-Ag | Dog/Canine | Dog/Canine CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T10965-Ag | Bovines/Cattle | Bovines/Cattle CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T10965-Ag | Equine/Horse | Equine/Horse CD62P/P-selectin/SELP VLP (virus-like particle) | HEK293 | Products Developing |