CD4 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore CD4 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]

Target ID GM-T10191
Target Name CD4
Gene Group ldentifer
(Target Gene ID in Homo species)
920
Gene ID 100052502 (Equus caballus), 12504 (Mus musculus), 24932 (Rattus norvegicus), 403931 (Canis lupus familiaris)
407098 (Bos taurus), 493775 (Felis catus), 713807 (Macaca mulatta), 920 (Homo sapiens)
Target Alternative Names CD4,CD4mut,Cd4,IMD79,L3T4,Leu-3,Ly-4,OKT4D,T-cell surface antigen T4/Leu-3,T-cell surface glycoprotein CD4,T4,W3/25,p55
Uniprot Accession P06332,P05540,P33705,P16003,P01730
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target, INN Index
Disease from KEGG Cytokine-cytokine receptor interaction, Cell adhesion molecules, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Yersinia infection, Human T-cell leukemia virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer
Gene Ensembl ENSECAG00000009049, ENSMUSG00000023274, ENSCAFG00845027739, ENSBTAG00000003255, ENSMMUG00000013202, ENSG00000010610
Target Classification Checkpoint-Immuno Oncology


Pre-made viral vector of CD4 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP004095Human CD4/CD4mut Lentivirus plasmidBC025782920HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP000215Human CD4/CD4mut Adenovirus plasmidBC025782920HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMLP004095Human CD4/CD4mut Lentivirus particleBC025782920HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP000215Human CD4/CD4mut Adenovirus particleBC025782920HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail


CD4 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo920Pre-made Human CD4/T4/IMD79 siRNA oligo Duplex920HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24932Pre-made Rat Cd4/p55/W3/25 siRNA oligo Duplex24932RatIn-vitro grade; in-vivo gradeDetail
pGMoligo12504Pre-made Mouse Cd4/L3T4/Ly-4 siRNA oligo Duplex12504MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo713807Pre-made Cynomolgus/Rhesus macaque CD4 siRNA oligo Duplex713807Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo493775Pre-made Cat/Feline CD4 siRNA oligo Duplex493775Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403931Pre-made Dog/Canine CD4 siRNA oligo Duplex403931Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo407098Pre-made Bovines/Cattle CD4 siRNA oligo Duplex407098Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100052502Pre-made Equine/Horse CD4 siRNA oligo Duplex100052502Equine/HorseIn-vitro grade; in-vivo gradeDetail


CD4 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T10191-AbHumanAnti-Human CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T10191-AbRatAnti-Rat CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T10191-AbMouseAnti-Mouse CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T10191-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T10191-AbCat/FelineAnti-Cat/Feline CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T10191-AbDog/CanineAnti-Dog/Canine CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T10191-AbBovines/CattleAnti-Bovines/Cattle CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T10191-AbEquine/HorseAnti-Equine/Horse CD4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


CD4 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T10191-AgHumanHuman CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T10191-AgRatRat CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T10191-AgMouseMouse CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T10191-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T10191-AgCat/FelineCat/Feline CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T10191-AgDog/CanineDog/Canine CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T10191-AgBovines/CattleBovines/Cattle CD4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T10191-AgEquine/HorseEquine/Horse CD4 VLP (virus-like particle)HEK293Products Developing