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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T10147
|
| Target Name |
PTPRS/R-PTP-sigma
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5802
|
| Gene ID |
101083913 (Felis catus), 102149682 (Equus caballus), 19280 (Mus musculus), 25529 (Rattus norvegicus)
485030 (Canis lupus familiaris), 537480 (Bos taurus), 574274 (Macaca mulatta), 5802 (Homo sapiens)
|
| Target Alternative Names |
Larptp2,PTP,PTP-NU3,PTP-sigma,PTPNU-3,PTPRS,PTPSIGMA,PTPsigma,Ptprd,Ptprs,Ptpsigma,Ptpsigma.,Ptpt9,R-PTP-S,R-PTP-sigma,RPTPsigma,Receptor-type tyrosine-protein phosphatase S,Receptor-type tyrosine-protein phosphatase sigma (R-PTP-sigma),Rptpd
|
| Uniprot Accession |
B0V2N1,Q64605,Q13332
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000032438, ENSMUSG00000013236, ENSCAFG00845013712, ENSBTAG00000018052, ENSMMUG00000011962, ENSG00000105426
|
PTPRS/R-PTP-sigma siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5802 | Pre-made Human PTPRS/R-PTP-S/PTPSIGMA siRNA oligo Duplex | 5802 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25529 | Pre-made Rat Ptprs/Ptprd/Rptpd siRNA oligo Duplex | 25529 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19280 | Pre-made Mouse Ptprs/PTP/Ptpt9 siRNA oligo Duplex | 19280 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574274 | Pre-made Cynomolgus/Rhesus macaque PTPRS siRNA oligo Duplex | 574274 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083913 | Pre-made Cat/Feline PTPRS siRNA oligo Duplex | 101083913 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485030 | Pre-made Dog/Canine PTPRS siRNA oligo Duplex | 485030 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo537480 | Pre-made Bovines/Cattle PTPRS siRNA oligo Duplex | 537480 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149682 | Pre-made Equine/Horse PTPRS siRNA oligo Duplex | 102149682 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTPRS/R-PTP-sigma antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T10147-Ab | Human | Anti-Human PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T10147-Ab | Rat | Anti-Rat PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T10147-Ab | Mouse | Anti-Mouse PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T10147-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T10147-Ab | Cat/Feline | Anti-Cat/Feline PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T10147-Ab | Dog/Canine | Anti-Dog/Canine PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T10147-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T10147-Ab | Equine/Horse | Anti-Equine/Horse PTPRS/R-PTP-sigma monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PTPRS/R-PTP-sigma VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T10147-Ag | Human | Human PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T10147-Ag | Rat | Rat PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T10147-Ag | Mouse | Mouse PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T10147-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T10147-Ag | Cat/Feline | Cat/Feline PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T10147-Ag | Dog/Canine | Dog/Canine PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T10147-Ag | Bovines/Cattle | Bovines/Cattle PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T10147-Ag | Equine/Horse | Equine/Horse PTPRS/R-PTP-sigma VLP (virus-like particle) | HEK293 | Products Developing |
