Explore SPARC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015]
| Target ID |
GM-T09439
|
| Target Name |
SPARC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6678
|
| Gene ID |
100060119 (Equus caballus), 100855736 (Canis lupus familiaris), 101099861 (Felis catus), 20692 (Mus musculus)
24791 (Rattus norvegicus), 282077 (Bos taurus), 6678 (Homo sapiens), 712388 (Macaca mulatta)
|
| Target Alternative Names |
BM-40,Basement-membrane protein 40 (BM-40),OI17,ON,ONT,Osteonectin (ON),SPARC,Secreted protein acidic and rich in cysteine,Sparc
|
| Uniprot Accession |
P07214,P16975,P13213,P09486
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000013874, ENSCAFG00845005166, ENSMUSG00000018593, ENSBTAG00000014835, ENSG00000113140, ENSMMUG00000053367
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of SPARC cDNA Clones/ORF Plasmid
SPARC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6678 | Pre-made Human SPARC/ON/ONT siRNA oligo Duplex | 6678 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24791 | Pre-made Rat Sparc siRNA oligo Duplex | 24791 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20692 | Pre-made Mouse Sparc/ON/BM-40 siRNA oligo Duplex | 20692 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712388 | Pre-made Cynomolgus/Rhesus macaque SPARC siRNA oligo Duplex | 712388 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099861 | Pre-made Cat/Feline SPARC siRNA oligo Duplex | 101099861 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855736 | Pre-made Dog/Canine SPARC siRNA oligo Duplex | 100855736 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282077 | Pre-made Bovines/Cattle SPARC siRNA oligo Duplex | 282077 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060119 | Pre-made Equine/Horse SPARC siRNA oligo Duplex | 100060119 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SPARC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T09439-Ab | Human | Anti-Human SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T09439-Ab | Rat | Anti-Rat SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T09439-Ab | Mouse | Anti-Mouse SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T09439-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T09439-Ab | Cat/Feline | Anti-Cat/Feline SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T09439-Ab | Dog/Canine | Anti-Dog/Canine SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T09439-Ab | Bovines/Cattle | Anti-Bovines/Cattle SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T09439-Ab | Equine/Horse | Anti-Equine/Horse SPARC monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SPARC VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T09439-Ag | Human | Human SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T09439-Ag | Rat | Rat SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T09439-Ag | Mouse | Mouse SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T09439-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T09439-Ag | Cat/Feline | Cat/Feline SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T09439-Ag | Dog/Canine | Dog/Canine SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T09439-Ag | Bovines/Cattle | Bovines/Cattle SPARC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T09439-Ag | Equine/Horse | Equine/Horse SPARC VLP (virus-like particle) | HEK293 | Products Developing |
