Explore TPBG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]
| Target ID |
GM-T09058
|
| Target Name |
TPBG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7162
|
| Gene ID |
100069910 (Equus caballus), 101085466 (Felis catus), 102156010 (Canis lupus familiaris), 21983 (Mus musculus)
540358 (Bos taurus), 693944 (Macaca mulatta), 7162 (Homo sapiens), 83684 (Rattus norvegicus)
|
| Target Alternative Names |
TPBG,Tpbg,5T4,WAIF1,M6P1,5T4AG
|
| Uniprot Accession |
Q9Z0L0,Q13641,Q5PQV5
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000044527, ENSMUSG00000035274, ENSBTAG00000039477, ENSMMUG00000063437, ENSG00000146242
|
| Target Classification |
Checkpoint-Immuno Oncology
|
TPBG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7162 | Pre-made Human TPBG/5T4/M6P1 siRNA oligo Duplex | 7162 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83684 | Pre-made Rat Tpbg/5T4/WAIF1 siRNA oligo Duplex | 83684 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21983 | Pre-made Mouse Tpbg/5T4/WAIF1 siRNA oligo Duplex | 21983 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693944 | Pre-made Cynomolgus/Rhesus macaque TPBG siRNA oligo Duplex | 693944 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085466 | Pre-made Cat/Feline TPBG siRNA oligo Duplex | 101085466 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102156010 | Pre-made Dog/Canine TPBG siRNA oligo Duplex | 102156010 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540358 | Pre-made Bovines/Cattle TPBG siRNA oligo Duplex | 540358 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069910 | Pre-made Equine/Horse TPBG siRNA oligo Duplex | 100069910 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TPBG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T09058-Ab | Human | Anti-Human TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T09058-Ab | Rat | Anti-Rat TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T09058-Ab | Mouse | Anti-Mouse TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T09058-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T09058-Ab | Cat/Feline | Anti-Cat/Feline TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T09058-Ab | Dog/Canine | Anti-Dog/Canine TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T09058-Ab | Bovines/Cattle | Anti-Bovines/Cattle TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T09058-Ab | Equine/Horse | Anti-Equine/Horse TPBG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TPBG VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T09058-Ag | Human | Human TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T09058-Ag | Rat | Rat TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T09058-Ag | Mouse | Mouse TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T09058-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T09058-Ag | Cat/Feline | Cat/Feline TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T09058-Ag | Dog/Canine | Dog/Canine TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T09058-Ag | Bovines/Cattle | Bovines/Cattle TPBG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T09058-Ag | Equine/Horse | Equine/Horse TPBG VLP (virus-like particle) | HEK293 | Products Developing |
