Explore ACACB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T08922
|
| Target Name |
ACACB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
32
|
| Gene ID |
100066740 (Equus caballus), 100685468 (Canis lupus familiaris), 100705 (Mus musculus), 101086680 (Felis catus)
116719 (Rattus norvegicus), 32 (Homo sapiens), 515338 (Bos taurus), 706909 (Macaca mulatta)
|
| Target Alternative Names |
ACACB,ACACbeta,ACC-beta,ACC2,ACCB,ACCbeta,Acacb,Acc2,Accb,Acetyl-CoA carboxylase 2,HACC275
|
| Uniprot Accession |
E9Q4Z2,O00763
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Adipocytokine signaling pathway, Insulin resistance, Alcoholic liver disease
|
| Gene Ensembl |
ENSECAG00000015548, ENSCAFG00845023823, ENSMUSG00000042010, ENSG00000076555, ENSMMUG00000022698
|
ACACB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo32 | Pre-made Human ACACB/ACC2/ACCB siRNA oligo Duplex | 32 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116719 | Pre-made Rat Acacb/Acc2 siRNA oligo Duplex | 116719 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100705 | Pre-made Mouse Acacb/Acc2/Accb siRNA oligo Duplex | 100705 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706909 | Pre-made Cynomolgus/Rhesus macaque ACACB siRNA oligo Duplex | 706909 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086680 | Pre-made Cat/Feline ACACB siRNA oligo Duplex | 101086680 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100685468 | Pre-made Dog/Canine ACACB siRNA oligo Duplex | 100685468 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515338 | Pre-made Bovines/Cattle ACACB siRNA oligo Duplex | 515338 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066740 | Pre-made Equine/Horse ACACB siRNA oligo Duplex | 100066740 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ACACB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T08922-Ab | Human | Anti-Human ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T08922-Ab | Rat | Anti-Rat ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T08922-Ab | Mouse | Anti-Mouse ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T08922-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T08922-Ab | Cat/Feline | Anti-Cat/Feline ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T08922-Ab | Dog/Canine | Anti-Dog/Canine ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T08922-Ab | Bovines/Cattle | Anti-Bovines/Cattle ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T08922-Ab | Equine/Horse | Anti-Equine/Horse ACACB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ACACB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T08922-Ag | Human | Human ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T08922-Ag | Rat | Rat ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T08922-Ag | Mouse | Mouse ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T08922-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T08922-Ag | Cat/Feline | Cat/Feline ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T08922-Ag | Dog/Canine | Dog/Canine ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T08922-Ag | Bovines/Cattle | Bovines/Cattle ACACB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T08922-Ag | Equine/Horse | Equine/Horse ACACB recombinant protein | Mammalian cell | Detail |
