Explore CD141/Thrombomodulin/THBD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T08583
|
| Target Name |
CD141/Thrombomodulin/THBD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7056
|
| Gene ID |
100049012 (Felis catus), 100146206 (Equus caballus), 21824 (Mus musculus), 281529 (Bos taurus)
474355 (Canis lupus familiaris), 702132 (Macaca mulatta), 7056 (Homo sapiens), 83580 (Rattus norvegicus)
|
| Target Alternative Names |
AHUS6,BDCA-3,BDCA3,CD141,Fetomodulin,THBD,THPH12,THRM,TM,Thbd,Thrombomodulin,fTM
|
| Uniprot Accession |
P15306,P06579,Q5W7P8,P07204
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Desmoplastic small round cell tumor (DSRCT), Mucocutaneous lymph node syndrome [Kawasaki], Sepsis
|
| Disease from KEGG |
Complement and coagulation cascades, AGE-RAGE signaling pathway in diabetic complications, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000005241, ENSMUSG00000074743, ENSCAFG00845027195, ENSMMUG00000016814, ENSG00000178726
|
Pre-made viral vector of CD141/Thrombomodulin/THBD cDNA Clones/ORF Plasmid
CD141/Thrombomodulin/THBD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7056 | Pre-made Human THBD/TM/THRM siRNA oligo Duplex | 7056 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83580 | Pre-made Rat Thbd siRNA oligo Duplex | 83580 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21824 | Pre-made Mouse Thbd/TM/CD141 siRNA oligo Duplex | 21824 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702132 | Pre-made Cynomolgus/Rhesus macaque THBD siRNA oligo Duplex | 702132 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100049012 | Pre-made Cat/Feline THBD/fTM siRNA oligo Duplex | 100049012 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474355 | Pre-made Dog/Canine THBD/TM siRNA oligo Duplex | 474355 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281529 | Pre-made Bovines/Cattle THBD siRNA oligo Duplex | 281529 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146206 | Pre-made Equine/Horse THBD siRNA oligo Duplex | 100146206 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD141/Thrombomodulin/THBD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T08583-Ab | Human | Anti-Human CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T08583-Ab | Rat | Anti-Rat CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T08583-Ab | Mouse | Anti-Mouse CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T08583-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T08583-Ab | Cat/Feline | Anti-Cat/Feline CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T08583-Ab | Dog/Canine | Anti-Dog/Canine CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T08583-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T08583-Ab | Equine/Horse | Anti-Equine/Horse CD141/Thrombomodulin/THBD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD141/Thrombomodulin/THBD VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T08583-Ag | Human | Human CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T08583-Ag | Rat | Rat CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T08583-Ag | Mouse | Mouse CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T08583-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T08583-Ag | Cat/Feline | Cat/Feline CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T08583-Ag | Dog/Canine | Dog/Canine CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T08583-Ag | Bovines/Cattle | Bovines/Cattle CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T08583-Ag | Equine/Horse | Equine/Horse CD141/Thrombomodulin/THBD VLP (virus-like particle) | HEK293 | Products Developing |
