Explore CFP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
| Target ID |
GM-T08029
|
| Target Name |
CFP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5199
|
| Gene ID |
100051317 (Equus caballus), 101090086 (Felis catus), 18636 (Mus musculus), 299314 (Rattus norvegicus)
491859 (Canis lupus familiaris), 5199 (Homo sapiens), 539605 (Bos taurus), 707386 (Macaca mulatta)
|
| Target Alternative Names |
BCFG,BFD,CFP,Cfp,Complement factor P,PFC,PFD,PROPERDIN,Pfc,Properdin
|
| Uniprot Accession |
P11680,P27918
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Proteinuria
|
| Gene Ensembl |
ENSECAG00000017644, ENSMUSG00000001128, ENSCAFG00845030596, ENSG00000126759, ENSBTAG00000015815, ENSMMUG00000032465
|
Pre-made viral vector of CFP cDNA Clones/ORF Plasmid
CFP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5199 | Pre-made Human CFP/BFD/PFC siRNA oligo Duplex | 5199 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo299314 | Pre-made Rat Cfp/Pfc siRNA oligo Duplex | 299314 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18636 | Pre-made Mouse Cfp/Pfc/BCFG siRNA oligo Duplex | 18636 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707386 | Pre-made Cynomolgus/Rhesus macaque CFP siRNA oligo Duplex | 707386 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090086 | Pre-made Cat/Feline CFP siRNA oligo Duplex | 101090086 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491859 | Pre-made Dog/Canine CFP siRNA oligo Duplex | 491859 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539605 | Pre-made Bovines/Cattle CFP siRNA oligo Duplex | 539605 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051317 | Pre-made Equine/Horse CFP siRNA oligo Duplex | 100051317 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CFP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T08029-Ab | Human | Anti-Human CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T08029-Ab | Rat | Anti-Rat CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T08029-Ab | Mouse | Anti-Mouse CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T08029-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T08029-Ab | Cat/Feline | Anti-Cat/Feline CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T08029-Ab | Dog/Canine | Anti-Dog/Canine CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T08029-Ab | Bovines/Cattle | Anti-Bovines/Cattle CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T08029-Ab | Equine/Horse | Anti-Equine/Horse CFP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CFP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T08029-Ag | Human | Human CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T08029-Ag | Rat | Rat CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T08029-Ag | Mouse | Mouse CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T08029-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T08029-Ag | Cat/Feline | Cat/Feline CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T08029-Ag | Dog/Canine | Dog/Canine CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T08029-Ag | Bovines/Cattle | Bovines/Cattle CFP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T08029-Ag | Equine/Horse | Equine/Horse CFP VLP (virus-like particle) | HEK293 | Products Developing |
