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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T08014
|
| Target Name |
TARDBP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
23435
|
| Gene ID |
100051482 (Equus caballus), 100423163 (Macaca mulatta), 101097257 (Felis catus), 230908 (Mus musculus) 23435 (Homo sapiens), 298648 (Rattus norvegicus), 478234 (Canis lupus familiaris), 540632 (Bos taurus)
|
| Target Alternative Names |
1190002A23Rik,ALS10,TAR DNA-binding protein 43,TARDBP,TDP-43,Tardbp,Tdp-43,Tdp43
|
| Uniprot Accession |
Q921F2,Q13148
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000008338, ENSMMUG00000007456, ENSMUSG00000041459, ENSG00000120948, ENSBTAG00000003697
|
Pre-made viral vector of TARDBP cDNA Clones/ORF Plasmid
TARDBP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23435 | Pre-made Human TARDBP/ALS10/TDP-43 siRNA oligo Duplex | 23435 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298648 | Pre-made Rat Tardbp/Tdp-43 siRNA oligo Duplex | 298648 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo230908 | Pre-made Mouse Tardbp/Tdp43/TDP-43 siRNA oligo Duplex | 230908 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100423163 | Pre-made Cynomolgus/Rhesus macaque TARDBP siRNA oligo Duplex | 100423163 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097257 | Pre-made Cat/Feline TARDBP siRNA oligo Duplex | 101097257 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478234 | Pre-made Dog/Canine TARDBP siRNA oligo Duplex | 478234 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540632 | Pre-made Bovines/Cattle TARDBP siRNA oligo Duplex | 540632 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051482 | Pre-made Equine/Horse TARDBP siRNA oligo Duplex | 100051482 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TARDBP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T08014-Ab | Human | Anti-Human TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T08014-Ab | Rat | Anti-Rat TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T08014-Ab | Mouse | Anti-Mouse TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T08014-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T08014-Ab | Cat/Feline | Anti-Cat/Feline TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T08014-Ab | Dog/Canine | Anti-Dog/Canine TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T08014-Ab | Bovines/Cattle | Anti-Bovines/Cattle TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T08014-Ab | Equine/Horse | Anti-Equine/Horse TARDBP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
TARDBP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T08014-Ag | Human | Human TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T08014-Ag | Rat | Rat TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T08014-Ag | Mouse | Mouse TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T08014-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T08014-Ag | Cat/Feline | Cat/Feline TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T08014-Ag | Dog/Canine | Dog/Canine TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T08014-Ag | Bovines/Cattle | Bovines/Cattle TARDBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T08014-Ag | Equine/Horse | Equine/Horse TARDBP recombinant protein | Mammalian cell | Detail |