Explore HTR1B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T07806
|
| Target Name |
HTR1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3351
|
| Gene ID |
100009680 (Equus caballus), 100144391 (Felis catus), 15551 (Mus musculus), 25075 (Rattus norvegicus)
317707 (Bos taurus), 3351 (Homo sapiens), 403741 (Canis lupus familiaris), 716704 (Macaca mulatta)
|
| Target Alternative Names |
5-HT-1B,5-HT-1D-beta,5-HT1B,5-HT1DB,5-hydroxytryptamine receptor 1B,HTR1B,HTR1D2,HTR1DB,Htr1b,S12,Serotonin 1D beta receptor (5-HT-1D-beta),Serotonin receptor 1B
|
| Uniprot Accession |
Q0EAB5,Q588Y6,P28334,P28564,P28222,P79250
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Schizophrenia, Alcoholism and substance abuse
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction
|
| Gene Ensembl |
ENSMUSG00000049511, ENSBTAG00000037429, ENSG00000135312, ENSCAFG00845008653, ENSMMUG00000015717
|
| Target Classification |
GPCR
|
Pre-made viral vector of HTR1B cDNA Clones/ORF Plasmid
HTR1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3351 | Pre-made Human HTR1B/S12/5-HT1B siRNA oligo Duplex | 3351 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25075 | Pre-made Rat Htr1b siRNA oligo Duplex | 25075 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15551 | Pre-made Mouse Htr1b/5-HT-1B siRNA oligo Duplex | 15551 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716704 | Pre-made Cynomolgus/Rhesus macaque HTR1B siRNA oligo Duplex | 716704 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100144391 | Pre-made Cat/Feline HTR1B siRNA oligo Duplex | 100144391 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403741 | Pre-made Dog/Canine HTR1B siRNA oligo Duplex | 403741 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317707 | Pre-made Bovines/Cattle HTR1B siRNA oligo Duplex | 317707 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009680 | Pre-made Equine/Horse HTR1B siRNA oligo Duplex | 100009680 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTR1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T07806-Ab | Human | Anti-Human HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T07806-Ab | Rat | Anti-Rat HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T07806-Ab | Mouse | Anti-Mouse HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T07806-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T07806-Ab | Cat/Feline | Anti-Cat/Feline HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T07806-Ab | Dog/Canine | Anti-Dog/Canine HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T07806-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T07806-Ab | Equine/Horse | Anti-Equine/Horse HTR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HTR1B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T07806-Ag | Human | Human HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T07806-Ag | Rat | Rat HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T07806-Ag | Mouse | Mouse HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T07806-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T07806-Ag | Cat/Feline | Cat/Feline HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T07806-Ag | Dog/Canine | Dog/Canine HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T07806-Ag | Bovines/Cattle | Bovines/Cattle HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T07806-Ag | Equine/Horse | Equine/Horse HTR1B VLP (virus-like particle) | HEK293 | Products Developing |
