Explore AGER/RAGE gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
| Target ID |
GM-T07400
|
| Target Name |
AGER/RAGE
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
177
|
| Gene ID |
100051699 (Equus caballus), 101096892 (Felis catus), 11596 (Mus musculus), 177 (Homo sapiens)
280986 (Bos taurus), 403168 (Canis lupus familiaris), 717296 (Macaca mulatta), 81722 (Rattus norvegicus)
|
| Target Alternative Names |
AGER,Advanced glycosylation end product-specific receptor,Ager,RAGE,Receptor for advanced glycosylation end products,SCARJ1,sRAGE
|
| Uniprot Accession |
Q62151,Q15109,Q28173,Q63495
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
AGE-RAGE signaling pathway in diabetic complications, Alzheimer disease, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000020819, ENSMUSG00000015452, ENSG00000204305, ENSBTAG00000014420, ENSCAFG00845014982, ENSMMUG00000018442
|
Pre-made viral vector of AGER/RAGE cDNA Clones/ORF Plasmid
AGER/RAGE siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo177 | Pre-made Human AGER/RAGE/sRAGE siRNA oligo Duplex | 177 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81722 | Pre-made Rat Ager/RAGE siRNA oligo Duplex | 81722 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11596 | Pre-made Mouse Ager/RAGE siRNA oligo Duplex | 11596 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717296 | Pre-made Cynomolgus/Rhesus macaque AGER siRNA oligo Duplex | 717296 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096892 | Pre-made Cat/Feline AGER siRNA oligo Duplex | 101096892 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403168 | Pre-made Dog/Canine AGER/RAGE siRNA oligo Duplex | 403168 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280986 | Pre-made Bovines/Cattle AGER/RAGE siRNA oligo Duplex | 280986 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051699 | Pre-made Equine/Horse AGER siRNA oligo Duplex | 100051699 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AGER/RAGE antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T07400-Ab | Human | Anti-Human AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T07400-Ab | Rat | Anti-Rat AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T07400-Ab | Mouse | Anti-Mouse AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T07400-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T07400-Ab | Cat/Feline | Anti-Cat/Feline AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T07400-Ab | Dog/Canine | Anti-Dog/Canine AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T07400-Ab | Bovines/Cattle | Anti-Bovines/Cattle AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T07400-Ab | Equine/Horse | Anti-Equine/Horse AGER/RAGE monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
AGER/RAGE VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T07400-Ag | Human | Human AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T07400-Ag | Rat | Rat AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T07400-Ag | Mouse | Mouse AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T07400-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T07400-Ag | Cat/Feline | Cat/Feline AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T07400-Ag | Dog/Canine | Dog/Canine AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T07400-Ag | Bovines/Cattle | Bovines/Cattle AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T07400-Ag | Equine/Horse | Equine/Horse AGER/RAGE VLP (virus-like particle) | HEK293 | Products Developing |
