Explore MAP4K2 gene products and cross-species
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
| Target ID |
GM-T07191
|
| Target Name |
MAP4K2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5871
|
| Gene ID |
100056001 (Equus caballus), 101094701 (Felis catus), 26412 (Mus musculus), 293694 (Rattus norvegicus)
483759 (Canis lupus familiaris), 520058 (Bos taurus), 5871 (Homo sapiens), 699331 (Macaca mulatta)
|
| Target Alternative Names |
B lymphocyte serine/threonine-protein kinase,BL44,GCK,Germinal center kinase (GC kinase),MAP4K2,MAPK/ERK kinase kinase kinase 2 (MEK kinase kinase 2,MEKKK 2),Map4k2,Mitogen-activated protein kinase kinase kinase kinase 2,RAB8IP,Rab8-interacting protein,Rab8ip
|
| Uniprot Accession |
Q61161,Q12851
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway
|
| Gene Ensembl |
ENSECAG00000007374, ENSMUSG00000024948, ENSCAFG00845028973, ENSBTAG00000001037, ENSG00000168067, ENSMMUG00000030597
|
Pre-made viral vector of MAP4K2 cDNA Clones/ORF Plasmid
MAP4K2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5871 | Pre-made Human MAP4K2/GCK/BL44 siRNA oligo Duplex | 5871 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo293694 | Pre-made Rat Map4k2 siRNA oligo Duplex | 293694 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26412 | Pre-made Mouse Map4k2/GCK/BL44 siRNA oligo Duplex | 26412 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699331 | Pre-made Cynomolgus/Rhesus macaque MAP4K2 siRNA oligo Duplex | 699331 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094701 | Pre-made Cat/Feline MAP4K2 siRNA oligo Duplex | 101094701 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483759 | Pre-made Dog/Canine MAP4K2 siRNA oligo Duplex | 483759 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520058 | Pre-made Bovines/Cattle MAP4K2 siRNA oligo Duplex | 520058 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056001 | Pre-made Equine/Horse MAP4K2 siRNA oligo Duplex | 100056001 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAP4K2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T07191-Ab | Human | Anti-Human MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T07191-Ab | Rat | Anti-Rat MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T07191-Ab | Mouse | Anti-Mouse MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T07191-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T07191-Ab | Cat/Feline | Anti-Cat/Feline MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T07191-Ab | Dog/Canine | Anti-Dog/Canine MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T07191-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T07191-Ab | Equine/Horse | Anti-Equine/Horse MAP4K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MAP4K2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T07191-Ag | Human | Human MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T07191-Ag | Rat | Rat MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T07191-Ag | Mouse | Mouse MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T07191-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T07191-Ag | Cat/Feline | Cat/Feline MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T07191-Ag | Dog/Canine | Dog/Canine MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T07191-Ag | Bovines/Cattle | Bovines/Cattle MAP4K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T07191-Ag | Equine/Horse | Equine/Horse MAP4K2 recombinant protein | Mammalian cell | Detail |
