Explore NTRK1/TrkA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T07173
|
| Target Name |
NTRK1/TrkA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4914
|
| Gene ID |
100064594 (Equus caballus), 101081603 (Felis catus), 18211 (Mus musculus), 353111 (Bos taurus)
490404 (Canis lupus familiaris), 4914 (Homo sapiens), 59109 (Rattus norvegicus), 719670 (Macaca mulatta)
|
| Target Alternative Names |
NTRK1,Ntrk1,Tkr,trk,TrkA,TRKA,MTC,TRK,TRK1,Trk-A,p140-TrkA,Trk
|
| Uniprot Accession |
Q3UFB7,P04629,P35739
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels, Pathways in cancer, Thyroid cancer, Central carbon metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000009460, ENSMUSG00000028072, ENSBTAG00000003060, ENSCAFG00845015005, ENSG00000198400, ENSMMUG00000012424
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of NTRK1/TrkA cDNA Clones/ORF Plasmid
NTRK1/TrkA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4914 | Pre-made Human NTRK1/MTC/TRK siRNA oligo Duplex | 4914 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo59109 | Pre-made Rat Ntrk1/Trk siRNA oligo Duplex | 59109 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18211 | Pre-made Mouse Ntrk1/Tkr/trk siRNA oligo Duplex | 18211 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719670 | Pre-made Cynomolgus/Rhesus macaque NTRK1 siRNA oligo Duplex | 719670 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081603 | Pre-made Cat/Feline NTRK1 siRNA oligo Duplex | 101081603 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490404 | Pre-made Dog/Canine NTRK1/TRKA siRNA oligo Duplex | 490404 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo353111 | Pre-made Bovines/Cattle NTRK1/TRKA siRNA oligo Duplex | 353111 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064594 | Pre-made Equine/Horse NTRK1 siRNA oligo Duplex | 100064594 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NTRK1/TrkA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T07173-Ab | Human | Anti-Human NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T07173-Ab | Rat | Anti-Rat NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T07173-Ab | Mouse | Anti-Mouse NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T07173-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T07173-Ab | Cat/Feline | Anti-Cat/Feline NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T07173-Ab | Dog/Canine | Anti-Dog/Canine NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T07173-Ab | Bovines/Cattle | Anti-Bovines/Cattle NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T07173-Ab | Equine/Horse | Anti-Equine/Horse NTRK1/TrkA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NTRK1/TrkA VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T07173-Ag | Human | Human NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T07173-Ag | Rat | Rat NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T07173-Ag | Mouse | Mouse NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T07173-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T07173-Ag | Cat/Feline | Cat/Feline NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T07173-Ag | Dog/Canine | Dog/Canine NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T07173-Ag | Bovines/Cattle | Bovines/Cattle NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T07173-Ag | Equine/Horse | Equine/Horse NTRK1/TrkA VLP (virus-like particle) | HEK293 | Products Developing |
