Explore HPD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
| Target ID |
GM-T07137
|
| Target Name |
HPD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3242
|
| Gene ID |
100059853 (Equus caballus), 101093465 (Felis catus), 15445 (Mus musculus), 29531 (Rattus norvegicus)
3242 (Homo sapiens), 516058 (Bos taurus), 610778 (Canis lupus familiaris), 700940 (Macaca mulatta)
|
| Target Alternative Names |
4-HPPD,4-hydroxyphenylpyruvate dioxygenase,4-hydroxyphenylpyruvic acid oxidase (4HPPD,4HPPD,Fla,Flp,GLOD3,HPD,HPPD,HPPDASE,HPPDase),Hpd,Hppd,Laf,PPD
|
| Uniprot Accession |
P49429,P32755,P32754,Q5EA20
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000011561, ENSMUSG00000029445, ENSG00000158104, ENSBTAG00000004175, ENSCAFG00845023604, ENSMMUG00000016454
|
Pre-made viral vector of HPD cDNA Clones/ORF Plasmid
HPD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3242 | Pre-made Human HPD/PPD/HPPD siRNA oligo Duplex | 3242 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29531 | Pre-made Rat Hpd siRNA oligo Duplex | 29531 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15445 | Pre-made Mouse Hpd/Fla/Flp siRNA oligo Duplex | 15445 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700940 | Pre-made Cynomolgus/Rhesus macaque HPD siRNA oligo Duplex | 700940 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093465 | Pre-made Cat/Feline HPD siRNA oligo Duplex | 101093465 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610778 | Pre-made Dog/Canine HPD siRNA oligo Duplex | 610778 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo516058 | Pre-made Bovines/Cattle HPD siRNA oligo Duplex | 516058 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059853 | Pre-made Equine/Horse HPD siRNA oligo Duplex | 100059853 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HPD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T07137-Ab | Human | Anti-Human HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T07137-Ab | Rat | Anti-Rat HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T07137-Ab | Mouse | Anti-Mouse HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T07137-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T07137-Ab | Cat/Feline | Anti-Cat/Feline HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T07137-Ab | Dog/Canine | Anti-Dog/Canine HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T07137-Ab | Bovines/Cattle | Anti-Bovines/Cattle HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T07137-Ab | Equine/Horse | Anti-Equine/Horse HPD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HPD recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T07137-Ag | Human | Human HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T07137-Ag | Rat | Rat HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T07137-Ag | Mouse | Mouse HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T07137-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T07137-Ag | Cat/Feline | Cat/Feline HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T07137-Ag | Dog/Canine | Dog/Canine HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T07137-Ag | Bovines/Cattle | Bovines/Cattle HPD recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T07137-Ag | Equine/Horse | Equine/Horse HPD recombinant protein | Mammalian cell | Detail |
