Explore eNOS/NOS3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
| Target ID |
GM-T06046
|
| Target Name |
eNOS/NOS3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4846
|
| Gene ID |
100063339 (Equus caballus), 101096463 (Felis catus), 18127 (Mus musculus), 24600 (Rattus norvegicus)
287024 (Bos taurus), 403784 (Canis lupus familiaris), 4846 (Homo sapiens), 714231 (Macaca mulatta)
|
| Target Alternative Names |
NOS3,Nos3,enos,eNOS,Nos-3,ecNOS,2310065A03Rik,eNos,NOS,ECNOS
|
| Uniprot Accession |
P70313,Q62600,P29473,Q9TUX8,P29474
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Calcium signaling pathway, cGMP-PKG signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Platelet activation, Oxytocin signaling pathway, Relaxin signaling pathway, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000024562, ENSMUSG00000028978, ENSBTAG00000017680, ENSG00000164867, ENSMMUG00000020437
|
| Target Classification |
Tumor-associated antigen (TAA)
|
eNOS/NOS3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4846 | Pre-made Human NOS3/eNOS/ECNOS siRNA oligo Duplex | 4846 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24600 | Pre-made Rat Nos3/eNos siRNA oligo Duplex | 24600 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18127 | Pre-made Mouse Nos3/eNOS/Nos-3 siRNA oligo Duplex | 18127 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714231 | Pre-made Cynomolgus/Rhesus macaque NOS3 siRNA oligo Duplex | 714231 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096463 | Pre-made Cat/Feline NOS3 siRNA oligo Duplex | 101096463 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403784 | Pre-made Dog/Canine NOS3/NOS siRNA oligo Duplex | 403784 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287024 | Pre-made Bovines/Cattle NOS3 siRNA oligo Duplex | 287024 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063339 | Pre-made Equine/Horse NOS3/enos siRNA oligo Duplex | 100063339 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
eNOS/NOS3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T06046-Ab | Human | Anti-Human eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T06046-Ab | Rat | Anti-Rat eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T06046-Ab | Mouse | Anti-Mouse eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T06046-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T06046-Ab | Cat/Feline | Anti-Cat/Feline eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T06046-Ab | Dog/Canine | Anti-Dog/Canine eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T06046-Ab | Bovines/Cattle | Anti-Bovines/Cattle eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T06046-Ab | Equine/Horse | Anti-Equine/Horse eNOS/NOS3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
eNOS/NOS3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T06046-Ag | Human | Human eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T06046-Ag | Rat | Rat eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T06046-Ag | Mouse | Mouse eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T06046-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T06046-Ag | Cat/Feline | Cat/Feline eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T06046-Ag | Dog/Canine | Dog/Canine eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T06046-Ag | Bovines/Cattle | Bovines/Cattle eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T06046-Ag | Equine/Horse | Equine/Horse eNOS/NOS3 recombinant protein | Mammalian cell | Detail |
