Explore CCKBR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]
| Target ID |
GM-T05849
|
| Target Name |
CCKBR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
887
|
| Gene ID |
100055073 (Equus caballus), 101098743 (Felis catus), 12426 (Mus musculus), 25706 (Rattus norvegicus)
281665 (Bos taurus), 485333 (Canis lupus familiaris), 712939 (Macaca mulatta), 887 (Homo sapiens)
|
| Target Alternative Names |
CCK-2R,CCK-B,CCK-B receptor,CCK-BR,CCK2-R,CCK2R,CCKBR,CCKR-2,Cck2r,Cckbr,Cholecystokinin-2 receptor (CCK2-R),Cholrec,GASR,Gastrin/cholecystokinin type B receptor
|
| Uniprot Accession |
P56481,P30553,P79266,P30552,P32239
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gastric acid secretion
|
| Gene Ensembl |
ENSECAG00000012751, ENSMUSG00000030898, ENSBTAG00000005236, ENSCAFG00845007238, ENSMMUG00000016884, ENSG00000110148
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CCKBR cDNA Clones/ORF Plasmid
CCKBR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo887 | Pre-made Human CCKBR/GASR/CCK-B siRNA oligo Duplex | 887 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25706 | Pre-made Rat Cckbr/Cck2r/Cholrec siRNA oligo Duplex | 25706 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12426 | Pre-made Mouse Cckbr/CCK2R/CCK-BR siRNA oligo Duplex | 12426 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712939 | Pre-made Cynomolgus/Rhesus macaque CCKBR siRNA oligo Duplex | 712939 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098743 | Pre-made Cat/Feline CCKBR siRNA oligo Duplex | 101098743 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485333 | Pre-made Dog/Canine CCKBR/CCK-BR/CCK2-R siRNA oligo Duplex | 485333 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281665 | Pre-made Bovines/Cattle CCKBR siRNA oligo Duplex | 281665 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055073 | Pre-made Equine/Horse CCKBR siRNA oligo Duplex | 100055073 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CCKBR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T05849-Ab | Human | Anti-Human CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T05849-Ab | Rat | Anti-Rat CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T05849-Ab | Mouse | Anti-Mouse CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T05849-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T05849-Ab | Cat/Feline | Anti-Cat/Feline CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T05849-Ab | Dog/Canine | Anti-Dog/Canine CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T05849-Ab | Bovines/Cattle | Anti-Bovines/Cattle CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T05849-Ab | Equine/Horse | Anti-Equine/Horse CCKBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CCKBR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T05849-Ag | Human | Human CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T05849-Ag | Rat | Rat CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T05849-Ag | Mouse | Mouse CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T05849-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T05849-Ag | Cat/Feline | Cat/Feline CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T05849-Ag | Dog/Canine | Dog/Canine CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T05849-Ag | Bovines/Cattle | Bovines/Cattle CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T05849-Ag | Equine/Horse | Equine/Horse CCKBR VLP (virus-like particle) | HEK293 | Products Developing |
