Explore LCAT gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T05661
|
| Target Name |
LCAT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3931
|
| Gene ID |
100053753 (Equus caballus), 101083225 (Felis catus), 16816 (Mus musculus), 24530 (Rattus norvegicus)
3931 (Homo sapiens), 479680 (Canis lupus familiaris), 510960 (Bos taurus), 701872 (Macaca mulatta)
|
| Target Alternative Names |
1-alkyl-2-acetylglycerophosphocholine esterase,D8Wsu61e,LCAT,Lcat,Lecithin-cholesterol acyltransferase,Phosphatidylcholine-sterol acyltransferase,Phospholipid-cholesterol acyltransferase,Platelet-activating factor acetylhydrolase (PAF acetylhydrolase)
|
| Uniprot Accession |
P16301,P18424,P04180
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Cholesterol metabolism, Glycerophospholipid metabolism
|
| Gene Ensembl |
ENSECAG00000022392, ENSMUSG00000035237, ENSG00000213398, ENSCAFG00845012245, ENSBTAG00000018043, ENSMMUG00000059923
|
| Target Classification |
|
Pre-made viral vector of LCAT cDNA Clones/ORF Plasmid
LCAT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3931 | Pre-made Human LCAT siRNA oligo Duplex | 3931 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24530 | Pre-made Rat Lcat siRNA oligo Duplex | 24530 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16816 | Pre-made Mouse Lcat/D8Wsu61e siRNA oligo Duplex | 16816 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701872 | Pre-made Cynomolgus/Rhesus macaque LCAT siRNA oligo Duplex | 701872 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083225 | Pre-made Cat/Feline LCAT siRNA oligo Duplex | 101083225 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479680 | Pre-made Dog/Canine LCAT siRNA oligo Duplex | 479680 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510960 | Pre-made Bovines/Cattle LCAT siRNA oligo Duplex | 510960 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053753 | Pre-made Equine/Horse LCAT siRNA oligo Duplex | 100053753 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LCAT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T05661-Ab | Human | Anti-Human LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T05661-Ab | Rat | Anti-Rat LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T05661-Ab | Mouse | Anti-Mouse LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T05661-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T05661-Ab | Cat/Feline | Anti-Cat/Feline LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T05661-Ab | Dog/Canine | Anti-Dog/Canine LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T05661-Ab | Bovines/Cattle | Anti-Bovines/Cattle LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T05661-Ab | Equine/Horse | Anti-Equine/Horse LCAT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LCAT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T05661-Ag | Human | Human LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T05661-Ag | Rat | Rat LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T05661-Ag | Mouse | Mouse LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T05661-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T05661-Ag | Cat/Feline | Cat/Feline LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T05661-Ag | Dog/Canine | Dog/Canine LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T05661-Ag | Bovines/Cattle | Bovines/Cattle LCAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T05661-Ag | Equine/Horse | Equine/Horse LCAT recombinant protein | Mammalian cell | Detail |
