Explore Neprilysin/CD10/MME gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T05409
|
| Target Name |
Neprilysin/CD10/MME
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4311
|
| Gene ID |
100053541 (Equus caballus), 101087516 (Felis catus), 17380 (Mus musculus), 24590 (Rattus norvegicus)
4311 (Homo sapiens), 477120 (Canis lupus familiaris), 536741 (Bos taurus), 707667 (Macaca mulatta)
|
| Target Alternative Names |
6030454K05Rik,Atriopeptidase,CALLA,CD10,CMT2T,Common acute lymphocytic leukemia antigen (CALLA),Enkephalinase,MME,Mme,NEP,Nep,Neprilysin,Neutral endopeptidase 24.11 (NEP,Neutral endopeptidase),SCA43,SFE,Skin fibroblast elastase (SFE),neprilysin
|
| Uniprot Accession |
Q61391,P07861,P08473
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Renal cell carcinoma
|
| Disease from KEGG |
Renin-angiotensin system, Hematopoietic cell lineage, Protein digestion and absorption, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000009138, ENSMUSG00000027820, ENSG00000196549, ENSCAFG00845020957, ENSBTAG00000002075, ENSMMUG00000006662
|
Pre-made viral vector of Neprilysin/CD10/MME cDNA Clones/ORF Plasmid
Neprilysin/CD10/MME siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4311 | Pre-made Human MME/NEP/SFE siRNA oligo Duplex | 4311 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24590 | Pre-made Rat Mme/Nep/SFE siRNA oligo Duplex | 24590 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17380 | Pre-made Mouse Mme/NEP/SFE siRNA oligo Duplex | 17380 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707667 | Pre-made Cynomolgus/Rhesus macaque MME/neprilysin siRNA oligo Duplex | 707667 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087516 | Pre-made Cat/Feline MME siRNA oligo Duplex | 101087516 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477120 | Pre-made Dog/Canine MME/CD10 siRNA oligo Duplex | 477120 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536741 | Pre-made Bovines/Cattle MME siRNA oligo Duplex | 536741 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053541 | Pre-made Equine/Horse MME siRNA oligo Duplex | 100053541 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Neprilysin/CD10/MME antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T05409-Ab | Human | Anti-Human Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T05409-Ab | Rat | Anti-Rat Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T05409-Ab | Mouse | Anti-Mouse Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T05409-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T05409-Ab | Cat/Feline | Anti-Cat/Feline Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T05409-Ab | Dog/Canine | Anti-Dog/Canine Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T05409-Ab | Bovines/Cattle | Anti-Bovines/Cattle Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T05409-Ab | Equine/Horse | Anti-Equine/Horse Neprilysin/CD10/MME monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Neprilysin/CD10/MME VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T05409-Ag | Human | Human Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T05409-Ag | Rat | Rat Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T05409-Ag | Mouse | Mouse Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T05409-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T05409-Ag | Cat/Feline | Cat/Feline Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T05409-Ag | Dog/Canine | Dog/Canine Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T05409-Ag | Bovines/Cattle | Bovines/Cattle Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T05409-Ag | Equine/Horse | Equine/Horse Neprilysin/CD10/MME VLP (virus-like particle) | HEK293 | Products Developing |
