Explore TGM2/TG2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T05387
|
| Target Name |
TGM2/TG2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7052
|
| Gene ID |
100070046 (Equus caballus), 101098215 (Felis catus), 21817 (Mus musculus), 281528 (Bos taurus)
485867 (Canis lupus familiaris), 56083 (Rattus norvegicus), 7052 (Homo sapiens), 706777 (Macaca mulatta)
|
| Target Alternative Names |
Erythrocyte transglutaminase,G(h),G[a]h,Heart G alpha(h) (hhG alpha(h)),Isopeptidase TGM2,Protein G alpha(h) (G(h)),Protein-glutamine deamidase TGM2,Protein-glutamine dopaminyltransferase TGM2,Protein-glutamine gamma-glutamyltransferase 2,Protein-glutamine histaminyltransferase TGM2,Protein-glutamine noradrenalinyltransferase TGM2,Protein-glutamine serotonyltransferase TGM2,TG,TG(C),TG2,TGC,TGII,TGM2,TGase C),TGase-2,TGase2,TgaseII,Tgm2,Tissue transglutaminase (tTG,Transglutaminase C (TG(C),Transglutaminase H (TGase H),Transglutaminase II (TGase II),Transglutaminase-2 (TG2,hTG2,hTG2),tTG,tTGas,tTgase)
|
| Uniprot Accession |
P21981,P51176,Q9WVJ6,P21980
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Gene Ensembl |
ENSECAG00000006290, ENSMUSG00000037820, ENSBTAG00000016208, ENSCAFG00845028869, ENSG00000198959, ENSMMUG00000018925
|
Pre-made viral vector of TGM2/TG2 cDNA Clones/ORF Plasmid
TGM2/TG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7052 | Pre-made Human TGM2/TGC/tTG siRNA oligo Duplex | 7052 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56083 | Pre-made Rat Tgm2/tTG/TGII siRNA oligo Duplex | 56083 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21817 | Pre-made Mouse Tgm2/TG2/tTG siRNA oligo Duplex | 21817 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706777 | Pre-made Cynomolgus/Rhesus macaque TGM2 siRNA oligo Duplex | 706777 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098215 | Pre-made Cat/Feline TGM2 siRNA oligo Duplex | 101098215 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485867 | Pre-made Dog/Canine TGM2 siRNA oligo Duplex | 485867 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281528 | Pre-made Bovines/Cattle TGM2/TG siRNA oligo Duplex | 281528 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070046 | Pre-made Equine/Horse TGM2 siRNA oligo Duplex | 100070046 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TGM2/TG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T05387-Ab | Human | Anti-Human TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T05387-Ab | Rat | Anti-Rat TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T05387-Ab | Mouse | Anti-Mouse TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T05387-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T05387-Ab | Cat/Feline | Anti-Cat/Feline TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T05387-Ab | Dog/Canine | Anti-Dog/Canine TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T05387-Ab | Bovines/Cattle | Anti-Bovines/Cattle TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T05387-Ab | Equine/Horse | Anti-Equine/Horse TGM2/TG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TGM2/TG2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T05387-Ag | Human | Human TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T05387-Ag | Rat | Rat TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T05387-Ag | Mouse | Mouse TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T05387-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T05387-Ag | Cat/Feline | Cat/Feline TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T05387-Ag | Dog/Canine | Dog/Canine TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T05387-Ag | Bovines/Cattle | Bovines/Cattle TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T05387-Ag | Equine/Horse | Equine/Horse TGM2/TG2 VLP (virus-like particle) | HEK293 | Products Developing |
