Explore Mast Cell Chymase/CMA1/CYM gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]
| Target ID |
GM-T05114
|
| Target Name |
Mast Cell Chymase/CMA1/CYM
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1215
|
| Gene ID |
101084796 (Felis catus), 1215 (Homo sapiens), 17228 (Mus musculus), 490628 (Canis lupus familiaris)
716395 (Macaca mulatta)
|
| Target Alternative Names |
Alpha-chymase,CMA1,CYH,CYM,Chymase,Cma1,MCT1,MMCP-5,Mast Cell Chymase,Mast cell protease I,Mcp-5,Mcp5,Mcpt5,chymase
|
| Uniprot Accession |
P23946,P21844,P21842
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Renin-angiotensin system
|
| Gene Ensembl |
ENSG00000092009, ENSMUSG00000022225, ENSCAFG00845008224, ENSMMUG00000019294
|
Pre-made viral vector of Mast Cell Chymase/CMA1/CYM cDNA Clones/ORF Plasmid
Mast Cell Chymase/CMA1/CYM siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1215 | Pre-made Human CMA1/CYH/MCT1 siRNA oligo Duplex | 1215 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17228 | Pre-made Mouse Cma1/Mcp5/Mcp-5 siRNA oligo Duplex | 17228 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716395 | Pre-made Cynomolgus/Rhesus macaque CMA1 siRNA oligo Duplex | 716395 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084796 | Pre-made Cat/Feline CMA1 siRNA oligo Duplex | 101084796 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490628 | Pre-made Dog/Canine CMA1 siRNA oligo Duplex | 490628 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
Mast Cell Chymase/CMA1/CYM antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T05114-Ab | Human | Anti-Human Mast Cell Chymase/CMA1/CYM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T05114-Ab | Mouse | Anti-Mouse Mast Cell Chymase/CMA1/CYM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T05114-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Mast Cell Chymase/CMA1/CYM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T05114-Ab | Cat/Feline | Anti-Cat/Feline Mast Cell Chymase/CMA1/CYM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T05114-Ab | Dog/Canine | Anti-Dog/Canine Mast Cell Chymase/CMA1/CYM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Mast Cell Chymase/CMA1/CYM recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T05114-Ag | Human | Human Mast Cell Chymase/CMA1/CYM recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T05114-Ag | Mouse | Mouse Mast Cell Chymase/CMA1/CYM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T05114-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Mast Cell Chymase/CMA1/CYM recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T05114-Ag | Cat/Feline | Cat/Feline Mast Cell Chymase/CMA1/CYM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T05114-Ag | Dog/Canine | Dog/Canine Mast Cell Chymase/CMA1/CYM recombinant protein | Mammalian cell | Detail |
