Explore EZH2 Y641F gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
| Target ID |
GM-T04512
|
| Target Name |
EZH2 Y641F
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2146
|
| Gene ID |
100051290 (Equus caballus), 101087309 (Felis catus), 14056 (Mus musculus), 2146 (Homo sapiens) 312299 (Rattus norvegicus), 475511 (Canis lupus familiaris), 509106 (Bos taurus), 709075 (Macaca mulatta)
|
| Target Alternative Names |
ENX-1,ENX1,EZH2,EZH2 Y641F,EZH2b,Enhancer of zeste homolog 2,Enx-1,Enx1h,Ezh2,Histone-lysine N-methyltransferase EZH2,KMT6,KMT6A,Lysine N-methyltransferase 6,WVS,WVS2,mKIAA4065
|
| Uniprot Accession |
Q61188,Q15910
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000021529, ENSMUSG00000029687, ENSG00000106462, ENSCAFG00845012096, ENSBTAG00000009426, ENSMMUG00000013494
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of EZH2 Y641F cDNA Clones/ORF Plasmid
EZH2 Y641F siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2146 | Pre-made Human EZH2/WVS/ENX1 siRNA oligo Duplex | 2146 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312299 | Pre-made Rat Ezh2 siRNA oligo Duplex | 312299 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14056 | Pre-made Mouse Ezh2/KMT6/Enx-1 siRNA oligo Duplex | 14056 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709075 | Pre-made Cynomolgus/Rhesus macaque EZH2 siRNA oligo Duplex | 709075 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087309 | Pre-made Cat/Feline EZH2 siRNA oligo Duplex | 101087309 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475511 | Pre-made Dog/Canine EZH2 siRNA oligo Duplex | 475511 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509106 | Pre-made Bovines/Cattle EZH2 siRNA oligo Duplex | 509106 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051290 | Pre-made Equine/Horse EZH2 siRNA oligo Duplex | 100051290 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EZH2 Y641F antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T04512-Ab | Human | Anti-Human EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-rg-T04512-Ab | Rat | Anti-Rat EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-mg-T04512-Ab | Mouse | Anti-Mouse EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-T04512-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-felg-T04512-Ab | Cat/Feline | Anti-Cat/Feline EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-cang-T04512-Ab | Dog/Canine | Anti-Dog/Canine EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-T04512-Ab | Bovines/Cattle | Anti-Bovines/Cattle EZH2 Y641F monoclonal antibody | mab | | Detail |
| GM-Tg-equg-T04512-Ab | Equine/Horse | Anti-Equine/Horse EZH2 Y641F monoclonal antibody | mab | | Detail |
EZH2 Y641F recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T04512-Ag | Human | Human EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T04512-Ag | Rat | Rat EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T04512-Ag | Mouse | Mouse EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T04512-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T04512-Ag | Cat/Feline | Cat/Feline EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T04512-Ag | Dog/Canine | Dog/Canine EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T04512-Ag | Bovines/Cattle | Bovines/Cattle EZH2 Y641F recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T04512-Ag | Equine/Horse | Equine/Horse EZH2 Y641F recombinant protein | Mammalian cell | Detail |