Explore LTA4H gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T03691
|
| Target Name |
LTA4H
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4048
|
| Gene ID |
100052257 (Equus caballus), 101083948 (Felis catus), 16993 (Mus musculus), 299732 (Rattus norvegicus)
4048 (Homo sapiens), 482611 (Canis lupus familiaris), 507130 (Bos taurus), 713038 (Macaca mulatta)
|
| Target Alternative Names |
LTA-4 hydrolase,LTA4H,Leukotriene A(4) hydrolase,Leukotriene A-4 hydrolase,Lta4h,Tripeptide aminopeptidase LTA4H
|
| Uniprot Accession |
P24527,P30349,P09960,Q3SZH7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Arachidonic acid metabolism
|
| Gene Ensembl |
ENSECAG00000008767, ENSMUSG00000015889, ENSG00000111144, ENSCAFG00845024692, ENSBTAG00000016415, ENSMMUG00000009312
|
Pre-made viral vector of LTA4H cDNA Clones/ORF Plasmid
LTA4H siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4048 | Pre-made Human LTA4H siRNA oligo Duplex | 4048 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo299732 | Pre-made Rat Lta4h siRNA oligo Duplex | 299732 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16993 | Pre-made Mouse Lta4h siRNA oligo Duplex | 16993 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713038 | Pre-made Cynomolgus/Rhesus macaque LTA4H siRNA oligo Duplex | 713038 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083948 | Pre-made Cat/Feline LTA4H siRNA oligo Duplex | 101083948 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482611 | Pre-made Dog/Canine LTA4H siRNA oligo Duplex | 482611 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507130 | Pre-made Bovines/Cattle LTA4H siRNA oligo Duplex | 507130 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052257 | Pre-made Equine/Horse LTA4H siRNA oligo Duplex | 100052257 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LTA4H antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T03691-Ab | Human | Anti-Human LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T03691-Ab | Rat | Anti-Rat LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T03691-Ab | Mouse | Anti-Mouse LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T03691-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T03691-Ab | Cat/Feline | Anti-Cat/Feline LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T03691-Ab | Dog/Canine | Anti-Dog/Canine LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T03691-Ab | Bovines/Cattle | Anti-Bovines/Cattle LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T03691-Ab | Equine/Horse | Anti-Equine/Horse LTA4H monoclonal antibody | mab | Therapeutics Target antibody | Detail |
LTA4H recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T03691-Ag | Human | Human LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T03691-Ag | Rat | Rat LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T03691-Ag | Mouse | Mouse LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T03691-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T03691-Ag | Cat/Feline | Cat/Feline LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T03691-Ag | Dog/Canine | Dog/Canine LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T03691-Ag | Bovines/Cattle | Bovines/Cattle LTA4H recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T03691-Ag | Equine/Horse | Equine/Horse LTA4H recombinant protein | Mammalian cell | Detail |
