Explore RSK2/RPS6KA3/RSK3 gene products and cross-species
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]
| Target ID |
GM-T03279
|
| Target Name |
RSK2/RPS6KA3/RSK3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6197
|
| Gene ID |
100058911 (Equus caballus), 101082546 (Felis catus), 110651 (Mus musculus), 119868388 (Canis lupus familiaris)
501560 (Rattus norvegicus), 511190 (Bos taurus), 6197 (Homo sapiens), 696825 (Macaca mulatta)
|
| Target Alternative Names |
90 kDa ribosomal protein S6 kinase 3 (p90-RSK 3,CLS,HU-3,ISPK-1,Insulin-stimulated protein kinase 1 (ISPK-1),MAP kinase-activated protein kinase 1b (MAPK-activated protein kinase 1b,MAPKAP kinase 1b,MAPKAPK-1b,MAPKAPK-1b),MAPKAPK1B,MPK-9,MRX19,RGD1563860,RPS6KA3,RSK,RSK2,RSK3,Ribosomal S6 kinase 2 (RSK-2),Ribosomal protein S6 kinase alpha-3,Rps6ka3,Rsk2,S6K-alpha-3,S6K-alpha3,XLID19,p90-RSK2,p90RSK3,p90RSK3),pp90RSK2
|
| Uniprot Accession |
P18654,P51812
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Insulin resistance, Yersinia infection, Chemical carcinogenesis - receptor activation
|
| Gene Ensembl |
ENSECAG00000011322, ENSMUSG00000031309, ENSCAFG00845029219, ENSBTAG00000017639, ENSG00000177189, ENSMMUG00000002134
|
| Target Classification |
Kinase
|
Pre-made viral vector of RSK2/RPS6KA3/RSK3 cDNA Clones/ORF Plasmid
RSK2/RPS6KA3/RSK3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6197 | Pre-made Human RPS6KA3/CLS/RSK siRNA oligo Duplex | 6197 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo501560 | Pre-made Rat Rps6ka3/RGD1563860 siRNA oligo Duplex | 501560 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110651 | Pre-made Mouse Rps6ka3/Rsk2/MPK-9 siRNA oligo Duplex | 110651 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696825 | Pre-made Cynomolgus/Rhesus macaque RPS6KA3 siRNA oligo Duplex | 696825 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082546 | Pre-made Cat/Feline RPS6KA3 siRNA oligo Duplex | 101082546 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119868388 | Pre-made Dog/Canine RPS6KA3 siRNA oligo Duplex | 119868388 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511190 | Pre-made Bovines/Cattle RPS6KA3 siRNA oligo Duplex | 511190 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058911 | Pre-made Equine/Horse RPS6KA3 siRNA oligo Duplex | 100058911 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RSK2/RPS6KA3/RSK3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T03279-Ab | Human | Anti-Human RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T03279-Ab | Rat | Anti-Rat RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T03279-Ab | Mouse | Anti-Mouse RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T03279-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T03279-Ab | Cat/Feline | Anti-Cat/Feline RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T03279-Ab | Dog/Canine | Anti-Dog/Canine RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T03279-Ab | Bovines/Cattle | Anti-Bovines/Cattle RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T03279-Ab | Equine/Horse | Anti-Equine/Horse RSK2/RPS6KA3/RSK3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RSK2/RPS6KA3/RSK3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T03279-Ag | Human | Human RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T03279-Ag | Rat | Rat RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T03279-Ag | Mouse | Mouse RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T03279-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T03279-Ag | Cat/Feline | Cat/Feline RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T03279-Ag | Dog/Canine | Dog/Canine RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T03279-Ag | Bovines/Cattle | Bovines/Cattle RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T03279-Ag | Equine/Horse | Equine/Horse RSK2/RPS6KA3/RSK3 recombinant protein | Mammalian cell | Detail |
