Explore IL-1RAP/IL1RAP gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
| Target ID |
GM-T02974
|
| Target Name |
IL-1RAP/IL1RAP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3556
|
| Gene ID |
100068726 (Equus caballus), 101094125 (Felis catus), 16180 (Mus musculus), 25466 (Rattus norvegicus) 3556 (Homo sapiens), 488126 (Canis lupus familiaris), 539334 (Bos taurus), 574387 (Macaca mulatta)
|
| Target Alternative Names |
6430709H04Rik,C3orf13,IL-1 receptor accessory protein,IL-1R3),IL-1RAP,IL-1RAcP,IL-1RAcp,IL1R3,IL1RAP,Il1racpb,Il1rap,Interleukin-1 receptor 3 (IL-1R-3,Interleukin-1 receptor accessory protein
|
| Uniprot Accession |
Q61730,Q63621,Q9NPH3,P59822
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease from KEGG |
MAPK signaling pathway, Cytokine-cytokine receptor interaction, Th17 cell differentiation, Inflammatory mediator regulation of TRP channels
|
| Gene Ensembl |
ENSECAG00000005083, ENSMUSG00000022514, ENSG00000196083, ENSCAFG00845024451, ENSBTAG00000013205, ENSMMUG00000022562
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
IL-1RAP/IL1RAP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3556 | Pre-made Human IL1RAP/IL1R3/C3orf13 siRNA oligo Duplex | 3556 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25466 | Pre-made Rat Il1rap/IL-1RAcp/Il1racpb siRNA oligo Duplex | 25466 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16180 | Pre-made Mouse Il1rap/IL-1RAcP/6430709H04Rik siRNA oligo Duplex | 16180 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574387 | Pre-made Cynomolgus/Rhesus macaque IL1RAP siRNA oligo Duplex | 574387 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094125 | Pre-made Cat/Feline IL1RAP siRNA oligo Duplex | 101094125 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488126 | Pre-made Dog/Canine IL1RAP siRNA oligo Duplex | 488126 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539334 | Pre-made Bovines/Cattle IL1RAP siRNA oligo Duplex | 539334 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068726 | Pre-made Equine/Horse IL1RAP siRNA oligo Duplex | 100068726 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1RAP/IL1RAP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02974-Ab | Human | Anti-Human IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T02974-Ab | Rat | Anti-Rat IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T02974-Ab | Mouse | Anti-Mouse IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T02974-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T02974-Ab | Cat/Feline | Anti-Cat/Feline IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T02974-Ab | Dog/Canine | Anti-Dog/Canine IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T02974-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T02974-Ab | Equine/Horse | Anti-Equine/Horse IL-1RAP/IL1RAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-1RAP/IL1RAP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02974-Ag | Human | Human IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02974-Ag | Rat | Rat IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02974-Ag | Mouse | Mouse IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02974-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02974-Ag | Cat/Feline | Cat/Feline IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02974-Ag | Dog/Canine | Dog/Canine IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02974-Ag | Bovines/Cattle | Bovines/Cattle IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02974-Ag | Equine/Horse | Equine/Horse IL-1RAP/IL1RAP VLP (virus-like particle) | HEK293 | Products Developing |