Explore iNOS/NOS2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T02703
|
| Target Name |
iNOS/NOS2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4843
|
| Gene ID |
101087020 (Felis catus), 18126 (Mus musculus), 24599 (Rattus norvegicus), 282876 (Bos taurus)
403822 (Canis lupus familiaris), 4843 (Homo sapiens), 706921 (Macaca mulatta), 791246 (Equus caballus)
|
| Target Alternative Names |
HEP-NOS,Hepatocyte NOS (HEP-NOS),INOS,Inducible NO synthase (Inducible NOS,MAC-NOS,NOS,NOS type II,NOS-II,NOS2,NOS2A,Nitric oxide synthase,Nos-2,Nos2,Nos2a,Peptidyl-cysteine S-nitrosylase NOS2,i-NOS,iNOS,iNOS),iNos,inducible
|
| Uniprot Accession |
P29477,Q06518,Q27995,O62699,P35228,O46660
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Calcium signaling pathway, HIF-1 signaling pathway, Relaxin signaling pathway, Alzheimer disease, Pertussis, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Pathways in cancer, Small cell lung cancer
|
| Gene Ensembl |
ENSMUSG00000020826, ENSBTAG00000006894, ENSCAFG00845014798, ENSG00000007171, ENSMMUG00000010083, ENSECAG00000024761
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of iNOS/NOS2 cDNA Clones/ORF Plasmid
iNOS/NOS2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4843 | Pre-made Human NOS2/NOS/INOS siRNA oligo Duplex | 4843 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24599 | Pre-made Rat Nos2/iNos/Nos2a siRNA oligo Duplex | 24599 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18126 | Pre-made Mouse Nos2/iNOS/Nos-2 siRNA oligo Duplex | 18126 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706921 | Pre-made Cynomolgus/Rhesus macaque NOS2/INOS/NOS2A siRNA oligo Duplex | 706921 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087020 | Pre-made Cat/Feline NOS2 siRNA oligo Duplex | 101087020 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403822 | Pre-made Dog/Canine NOS2/INOS/NOS2A siRNA oligo Duplex | 403822 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282876 | Pre-made Bovines/Cattle NOS2/iNOS/NOS2A siRNA oligo Duplex | 282876 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo791246 | Pre-made Equine/Horse NOS2/INOS siRNA oligo Duplex | 791246 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
iNOS/NOS2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02703-Ab | Human | Anti-Human iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02703-Ab | Rat | Anti-Rat iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02703-Ab | Mouse | Anti-Mouse iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02703-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02703-Ab | Cat/Feline | Anti-Cat/Feline iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02703-Ab | Dog/Canine | Anti-Dog/Canine iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02703-Ab | Bovines/Cattle | Anti-Bovines/Cattle iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02703-Ab | Equine/Horse | Anti-Equine/Horse iNOS/NOS2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
iNOS/NOS2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02703-Ag | Human | Human iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T02703-Ag | Rat | Rat iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T02703-Ag | Mouse | Mouse iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T02703-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T02703-Ag | Cat/Feline | Cat/Feline iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T02703-Ag | Dog/Canine | Dog/Canine iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T02703-Ag | Bovines/Cattle | Bovines/Cattle iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T02703-Ag | Equine/Horse | Equine/Horse iNOS/NOS2 recombinant protein | Mammalian cell | Detail |
