Explore SLCO1B3/OATP1B3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
| Target ID |
GM-T02565
|
| Target Name |
SLCO1B3/OATP1B3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
28234
|
| Gene ID |
28234 (Homo sapiens), 28253 (Mus musculus), 403519 (Canis lupus familiaris), 574354 (Macaca mulatta)
58978 (Rattus norvegicus)
|
| Target Alternative Names |
SLCO1B3,Slco1b2,SLCO1B2,LST3,HBLRR,LST-2,OATP8,OATP-8,OATP1B3,SLC21A8,LST-3TM13,OATP2,Oatp4,lst-1,OATP-C,mlst-1,Oatp1b2,Slc21a6,Slc21a10,7330442B20Rik,OATPC,Oatp1b4,Slco1b4,OATP-4,rlst-1,Slco1b3
|
| Uniprot Accession |
Q9NPD5,Q9JJL3,Q9QZX8
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Bile secretion
|
| Gene Ensembl |
ENSG00000111700, ENSMUSG00000030236, ENSCAFG00845015602, ENSMMUG00000020443
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of SLCO1B3/OATP1B3 cDNA Clones/ORF Plasmid
SLCO1B3/OATP1B3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo28234 | Pre-made Human SLCO1B3/LST3/HBLRR siRNA oligo Duplex | 28234 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58978 | Pre-made Rat Slco1b2/Oatp4/OATP-4 siRNA oligo Duplex | 58978 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo28253 | Pre-made Mouse Slco1b2/OATP2/Oatp4 siRNA oligo Duplex | 28253 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574354 | Pre-made Cynomolgus/Rhesus macaque SLCO1B3 siRNA oligo Duplex | 574354 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403519 | Pre-made Dog/Canine SLCO1B2/OATPC/Oatp1b4 siRNA oligo Duplex | 403519 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
SLCO1B3/OATP1B3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02565-Ab | Human | Anti-Human SLCO1B3/OATP1B3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02565-Ab | Rat | Anti-Rat SLCO1B3/OATP1B3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02565-Ab | Mouse | Anti-Mouse SLCO1B3/OATP1B3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02565-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLCO1B3/OATP1B3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02565-Ab | Dog/Canine | Anti-Dog/Canine SLCO1B3/OATP1B3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SLCO1B3/OATP1B3 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02565-Ag | Human | Human SLCO1B3/OATP1B3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02565-Ag | Rat | Rat SLCO1B3/OATP1B3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02565-Ag | Mouse | Mouse SLCO1B3/OATP1B3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02565-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLCO1B3/OATP1B3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02565-Ag | Dog/Canine | Dog/Canine SLCO1B3/OATP1B3 VLP (virus-like particle) | HEK293 | Products Developing |
