Explore DRD3/D3R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
| Target ID |
GM-T02551
|
| Target Name |
DRD3/D3R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1814
|
| Gene ID |
100061160 (Equus caballus), 100425047 (Macaca mulatta), 101092878 (Felis catus), 13490 (Mus musculus)
1814 (Homo sapiens), 29238 (Rattus norvegicus), 487984 (Canis lupus familiaris), 537043 (Bos taurus)
|
| Target Alternative Names |
D(3) dopamine receptor,D3DR,D3R,DRD3,Dopamine D3 receptor,Drd3,ETM1,FET1
|
| Uniprot Accession |
P30728,P35462,P19020
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000016540, ENSMMUG00000022936, ENSMUSG00000022705, ENSG00000151577, ENSCAFG00845015031, ENSBTAG00000002132
|
| Target Classification |
GPCR
|
Pre-made viral vector of DRD3/D3R cDNA Clones/ORF Plasmid
DRD3/D3R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1814 | Pre-made Human DRD3/D3DR/ETM1 siRNA oligo Duplex | 1814 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29238 | Pre-made Rat Drd3 siRNA oligo Duplex | 29238 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13490 | Pre-made Mouse Drd3/D3R siRNA oligo Duplex | 13490 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100425047 | Pre-made Cynomolgus/Rhesus macaque DRD3 siRNA oligo Duplex | 100425047 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092878 | Pre-made Cat/Feline DRD3 siRNA oligo Duplex | 101092878 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487984 | Pre-made Dog/Canine DRD3 siRNA oligo Duplex | 487984 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo537043 | Pre-made Bovines/Cattle DRD3 siRNA oligo Duplex | 537043 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061160 | Pre-made Equine/Horse DRD3 siRNA oligo Duplex | 100061160 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DRD3/D3R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02551-Ab | Human | Anti-Human DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02551-Ab | Rat | Anti-Rat DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02551-Ab | Mouse | Anti-Mouse DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02551-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02551-Ab | Cat/Feline | Anti-Cat/Feline DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02551-Ab | Dog/Canine | Anti-Dog/Canine DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02551-Ab | Bovines/Cattle | Anti-Bovines/Cattle DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02551-Ab | Equine/Horse | Anti-Equine/Horse DRD3/D3R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DRD3/D3R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02551-Ag | Human | Human DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02551-Ag | Rat | Rat DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02551-Ag | Mouse | Mouse DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02551-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02551-Ag | Cat/Feline | Cat/Feline DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02551-Ag | Dog/Canine | Dog/Canine DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02551-Ag | Bovines/Cattle | Bovines/Cattle DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02551-Ag | Equine/Horse | Equine/Horse DRD3/D3R VLP (virus-like particle) | HEK293 | Products Developing |
