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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T02446
|
| Target Name |
EPHB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2047
|
| Gene ID |
100053254 (Equus caballus), 101086086 (Felis catus), 2047 (Homo sapiens), 24338 (Rattus norvegicus)
270190 (Mus musculus), 485671 (Canis lupus familiaris), 534731 (Bos taurus), 717211 (Macaca mulatta)
|
| Target Alternative Names |
9330129L11,C130099E04Rik,Cek6,ELK,EPH tyrosine kinase 2,EPH-like kinase 6 (EK6,EPHB1,EPHT2,Elk,Elkh,Ephb1,Ephb2,Ephrin type-B receptor 1,Erk,Hek6,NET,Net,Neuronally-expressed EPH-related tyrosine kinase (NET),Tyrosine-protein kinase receptor EPH-2,elk,hEK6)
|
| Uniprot Accession |
P54762,P09759,Q8CBF3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000013862, ENSG00000154928, ENSMUSG00000032537, ENSCAFG00845019520, ENSBTAG00000015377, ENSMMUG00000021334
|
| Target Classification |
Kinase
|
Pre-made viral vector of EPHB1 cDNA Clones/ORF Plasmid
EPHB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2047 | Pre-made Human EPHB1/ELK/NET siRNA oligo Duplex | 2047 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24338 | Pre-made Rat Ephb1/Erk/elk siRNA oligo Duplex | 24338 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo270190 | Pre-made Mouse Ephb1/Elk/Net siRNA oligo Duplex | 270190 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717211 | Pre-made Cynomolgus/Rhesus macaque EPHB1 siRNA oligo Duplex | 717211 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086086 | Pre-made Cat/Feline EPHB1 siRNA oligo Duplex | 101086086 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485671 | Pre-made Dog/Canine EPHB1 siRNA oligo Duplex | 485671 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534731 | Pre-made Bovines/Cattle EPHB1 siRNA oligo Duplex | 534731 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053254 | Pre-made Equine/Horse EPHB1 siRNA oligo Duplex | 100053254 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EPHB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02446-Ab | Human | Anti-Human EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02446-Ab | Rat | Anti-Rat EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02446-Ab | Mouse | Anti-Mouse EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02446-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02446-Ab | Cat/Feline | Anti-Cat/Feline EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02446-Ab | Dog/Canine | Anti-Dog/Canine EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02446-Ab | Bovines/Cattle | Anti-Bovines/Cattle EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02446-Ab | Equine/Horse | Anti-Equine/Horse EPHB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EPHB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02446-Ag | Human | Human EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02446-Ag | Rat | Rat EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02446-Ag | Mouse | Mouse EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02446-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02446-Ag | Cat/Feline | Cat/Feline EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02446-Ag | Dog/Canine | Dog/Canine EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02446-Ag | Bovines/Cattle | Bovines/Cattle EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02446-Ag | Equine/Horse | Equine/Horse EPHB1 VLP (virus-like particle) | HEK293 | Products Developing |
