Explore EIF2AK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
| Target ID |
GM-T02439
|
| Target Name |
EIF2AK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27102
|
| Gene ID |
100062309 (Equus caballus), 100302056 (Canis lupus familiaris), 101081103 (Felis catus), 15467 (Mus musculus)
27102 (Homo sapiens), 27137 (Rattus norvegicus), 507689 (Bos taurus), 703325 (Macaca mulatta)
|
| Target Alternative Names |
EIF2AK1,Eif2ak1,Eukaryotic translation initiation factor 2-alpha kinase 1,HCR,HRI,Heme-controlled repressor (HCR),Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase,Heme-regulated inhibitor (hHRI),Hemin-sensitive initiation factor 2-alpha kinase,Hri,LEMSPAD,hHRI
|
| Uniprot Accession |
Q9Z2R9,Q9BQI3,Q63185
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, Hepatitis C, Measles
|
| Gene Ensembl |
ENSECAG00000007200, ENSCAFG00845010328, ENSMUSG00000029613, ENSG00000086232, ENSBTAG00000007370, ENSMMUG00000030419
|
| Target Classification |
Kinase
|
Pre-made viral vector of EIF2AK1 cDNA Clones/ORF Plasmid
EIF2AK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27102 | Pre-made Human EIF2AK1/HCR/HRI siRNA oligo Duplex | 27102 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo27137 | Pre-made Rat Eif2ak1/Hri siRNA oligo Duplex | 27137 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15467 | Pre-made Mouse Eif2ak1/HCR/Hri siRNA oligo Duplex | 15467 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703325 | Pre-made Cynomolgus/Rhesus macaque EIF2AK1 siRNA oligo Duplex | 703325 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081103 | Pre-made Cat/Feline EIF2AK1 siRNA oligo Duplex | 101081103 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100302056 | Pre-made Dog/Canine EIF2AK1 siRNA oligo Duplex | 100302056 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507689 | Pre-made Bovines/Cattle EIF2AK1 siRNA oligo Duplex | 507689 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062309 | Pre-made Equine/Horse EIF2AK1 siRNA oligo Duplex | 100062309 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EIF2AK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02439-Ab | Human | Anti-Human EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02439-Ab | Rat | Anti-Rat EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02439-Ab | Mouse | Anti-Mouse EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02439-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02439-Ab | Cat/Feline | Anti-Cat/Feline EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02439-Ab | Dog/Canine | Anti-Dog/Canine EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02439-Ab | Bovines/Cattle | Anti-Bovines/Cattle EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02439-Ab | Equine/Horse | Anti-Equine/Horse EIF2AK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
EIF2AK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02439-Ag | Human | Human EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T02439-Ag | Rat | Rat EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T02439-Ag | Mouse | Mouse EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T02439-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T02439-Ag | Cat/Feline | Cat/Feline EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T02439-Ag | Dog/Canine | Dog/Canine EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T02439-Ag | Bovines/Cattle | Bovines/Cattle EIF2AK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T02439-Ag | Equine/Horse | Equine/Horse EIF2AK1 recombinant protein | Mammalian cell | Detail |
