Explore BAFF/TNFSF13B/CD257 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
| Target ID |
GM-T02318
|
| Target Name |
BAFF/TNFSF13B/CD257
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10673
|
| Gene ID |
100051550 (Equus caballus), 101088640 (Felis catus), 10673 (Homo sapiens), 24099 (Mus musculus)
485545 (Canis lupus familiaris), 498666 (Rattus norvegicus), 504507 (Bos taurus), 693917 (Macaca mulatta)
|
| Target Alternative Names |
B lymphocyte stimulator (BLyS),B-cell-activating factor,BAFF,BLYS,BLyS,CD257,D8Ertd387e,DTL,Dendritic cell-derived TNF-like molecule,RGD1561519,TALL-1,TALL1,THANK,TNF- and APOL-related leukocyte expressed ligand 1 (TALL-1),TNFSF13B,TNFSF20,TNLG7A,Tnfsf13b,Tnlg7a,Tumor necrosis factor ligand superfamily member 13B,ZTNF4,zTNF4
|
| Uniprot Accession |
Q9Y275,Q9WU72
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease |
cancer, Lupus Glomerulonephritis
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000019758, ENSG00000102524, ENSMUSG00000031497, ENSBTAG00000011563, ENSMMUG00000008040
|
Pre-made viral vector of BAFF/TNFSF13B/CD257 cDNA Clones/ORF Plasmid
BAFF/TNFSF13B/CD257 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10673 | Pre-made Human TNFSF13B/DTL/BAFF siRNA oligo Duplex | 10673 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498666 | Pre-made Rat Tnfsf13b/BAFF/Tnlg7a siRNA oligo Duplex | 498666 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24099 | Pre-made Mouse Tnfsf13b/BAFF/BLyS siRNA oligo Duplex | 24099 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693917 | Pre-made Cynomolgus/Rhesus macaque TNFSF13B/TNLG7A siRNA oligo Duplex | 693917 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088640 | Pre-made Cat/Feline TNFSF13B siRNA oligo Duplex | 101088640 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485545 | Pre-made Dog/Canine TNFSF13B/TNLG7A siRNA oligo Duplex | 485545 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504507 | Pre-made Bovines/Cattle TNFSF13B/TNLG7A siRNA oligo Duplex | 504507 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051550 | Pre-made Equine/Horse TNFSF13B siRNA oligo Duplex | 100051550 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BAFF/TNFSF13B/CD257 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02318-Ab | Human | Anti-Human BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T02318-Ab | Rat | Anti-Rat BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T02318-Ab | Mouse | Anti-Mouse BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T02318-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T02318-Ab | Cat/Feline | Anti-Cat/Feline BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T02318-Ab | Dog/Canine | Anti-Dog/Canine BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T02318-Ab | Bovines/Cattle | Anti-Bovines/Cattle BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T02318-Ab | Equine/Horse | Anti-Equine/Horse BAFF/TNFSF13B/CD257 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
BAFF/TNFSF13B/CD257 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02318-Ag | Human | Human BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02318-Ag | Rat | Rat BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02318-Ag | Mouse | Mouse BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02318-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02318-Ag | Cat/Feline | Cat/Feline BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02318-Ag | Dog/Canine | Dog/Canine BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02318-Ag | Bovines/Cattle | Bovines/Cattle BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02318-Ag | Equine/Horse | Equine/Horse BAFF/TNFSF13B/CD257 VLP (virus-like particle) | HEK293 | Products Developing |
