Explore KCNT1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
| Target ID |
GM-T02262
|
| Target Name |
KCNT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
57582
|
| Gene ID |
100068421 (Equus caballus), 101091413 (Felis catus), 227632 (Mus musculus), 491258 (Canis lupus familiaris)
529468 (Bos taurus), 57582 (Homo sapiens), 60444 (Rattus norvegicus), 721830 (Macaca mulatta)
|
| Target Alternative Names |
C030030G16Rik,DEE14,EIEE14,ENFL5,KCNT1,KCa4.1,KNa1.1,Kcnt1,Potassium channel subfamily T member 1,SLACK,Slack,Slo2.2,Sodium and chloride-activated ATP-sensitive potassium channel Slo2.2,bA100C15.2,rSlo2,slo2
|
| Uniprot Accession |
Q6ZPR4,Q5JUK3,Q9Z258
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000003311, ENSMUSG00000058740, ENSCAFG00845007891, ENSBTAG00000018975, ENSG00000107147, ENSMMUG00000021496
|
KCNT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57582 | Pre-made Human KCNT1/DEE14/ENFL5 siRNA oligo Duplex | 57582 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60444 | Pre-made Rat Kcnt1/Slack/rSlo2 siRNA oligo Duplex | 60444 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo227632 | Pre-made Mouse Kcnt1/slo2/Slack siRNA oligo Duplex | 227632 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721830 | Pre-made Cynomolgus/Rhesus macaque KCNT1 siRNA oligo Duplex | 721830 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091413 | Pre-made Cat/Feline KCNT1 siRNA oligo Duplex | 101091413 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491258 | Pre-made Dog/Canine KCNT1 siRNA oligo Duplex | 491258 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529468 | Pre-made Bovines/Cattle KCNT1 siRNA oligo Duplex | 529468 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068421 | Pre-made Equine/Horse KCNT1 siRNA oligo Duplex | 100068421 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02262-Ab | Human | Anti-Human KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02262-Ab | Rat | Anti-Rat KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02262-Ab | Mouse | Anti-Mouse KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02262-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02262-Ab | Cat/Feline | Anti-Cat/Feline KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02262-Ab | Dog/Canine | Anti-Dog/Canine KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02262-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02262-Ab | Equine/Horse | Anti-Equine/Horse KCNT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNT1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02262-Ag | Human | Human KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02262-Ag | Rat | Rat KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02262-Ag | Mouse | Mouse KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02262-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02262-Ag | Cat/Feline | Cat/Feline KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02262-Ag | Dog/Canine | Dog/Canine KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02262-Ag | Bovines/Cattle | Bovines/Cattle KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02262-Ag | Equine/Horse | Equine/Horse KCNT1 VLP (virus-like particle) | HEK293 | Products Developing |
