Explore PDE4D gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
| Target ID |
GM-T02001
|
| Target Name |
PDE4D
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5144
|
| Gene ID |
100051344 (Equus caballus), 101092826 (Felis catus), 238871 (Mus musculus), 24627 (Rattus norvegicus)
487221 (Canis lupus familiaris), 5144 (Homo sapiens), 539556 (Bos taurus), 712180 (Macaca mulatta)
|
| Target Alternative Names |
3',5'-cyclic-AMP phosphodiesterase 4D,9630011N22Rik,ACRDYS2,DPDE3,Dpde3,HSPDE4D,PDE3/IVd,PDE43,PDE4D,PDE4DN2,Pde4d,STRK1,cAMP-specific phosphodiesterase 4D
|
| Uniprot Accession |
Q01063,P14270,Q08499
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000013771, ENSMUSG00000021699, ENSCAFG00845007091, ENSG00000113448, ENSBTAG00000000494, ENSMMUG00000012132
|
Pre-made viral vector of PDE4D cDNA Clones/ORF Plasmid
PDE4D siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5144 | Pre-made Human PDE4D/DPDE3/PDE43 siRNA oligo Duplex | 5144 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24627 | Pre-made Rat Pde4d/DPDE3/PDE3/IVd siRNA oligo Duplex | 24627 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo238871 | Pre-made Mouse Pde4d/Dpde3/9630011N22Rik siRNA oligo Duplex | 238871 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712180 | Pre-made Cynomolgus/Rhesus macaque PDE4D siRNA oligo Duplex | 712180 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092826 | Pre-made Cat/Feline PDE4D siRNA oligo Duplex | 101092826 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487221 | Pre-made Dog/Canine PDE4D siRNA oligo Duplex | 487221 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539556 | Pre-made Bovines/Cattle PDE4D siRNA oligo Duplex | 539556 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051344 | Pre-made Equine/Horse PDE4D siRNA oligo Duplex | 100051344 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDE4D antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02001-Ab | Human | Anti-Human PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02001-Ab | Rat | Anti-Rat PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02001-Ab | Mouse | Anti-Mouse PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02001-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02001-Ab | Cat/Feline | Anti-Cat/Feline PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02001-Ab | Dog/Canine | Anti-Dog/Canine PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02001-Ab | Bovines/Cattle | Anti-Bovines/Cattle PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02001-Ab | Equine/Horse | Anti-Equine/Horse PDE4D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PDE4D VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02001-Ag | Human | Human PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02001-Ag | Rat | Rat PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02001-Ag | Mouse | Mouse PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02001-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02001-Ag | Cat/Feline | Cat/Feline PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02001-Ag | Dog/Canine | Dog/Canine PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02001-Ag | Bovines/Cattle | Bovines/Cattle PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02001-Ag | Equine/Horse | Equine/Horse PDE4D VLP (virus-like particle) | HEK293 | Products Developing |
