Explore MST1R/RON/CD136 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T01973
|
| Target Name |
MST1R/RON/CD136
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4486
|
| Gene ID |
100062492 (Equus caballus), 101089993 (Felis catus), 19882 (Mus musculus), 300999 (Rattus norvegicus)
444854 (Canis lupus familiaris), 4486 (Homo sapiens), 525504 (Bos taurus), 704437 (Macaca mulatta)
|
| Target Alternative Names |
CD136,CDw136,Cdw136,Fv-2,Fv2,MSP receptor,MST1R,Macrophage-stimulating protein receptor,Mst1r,NPCA3,PTK8,Protein-tyrosine kinase 8,Ptk8,RON,RON/MST1R,Ron,SEA,STK,Stk,p185-Ron
|
| Uniprot Accession |
Q62190,Q04912
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease from KEGG |
Calcium signaling pathway
|
| Gene Ensembl |
ENSECAG00000024812, ENSMUSG00000032584, ENSCAFG00845023772, ENSG00000164078, ENSBTAG00000015046, ENSMMUG00000003353
|
| Target Classification |
Kinase, Checkpoint-Immuno Oncology
|
Pre-made viral vector of MST1R/RON/CD136 cDNA Clones/ORF Plasmid
MST1R/RON/CD136 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4486 | Pre-made Human MST1R/RON/SEA siRNA oligo Duplex | 4486 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo300999 | Pre-made Rat Mst1r/Ron/Stk siRNA oligo Duplex | 300999 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19882 | Pre-made Mouse Mst1r/Fv2/Ron siRNA oligo Duplex | 19882 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704437 | Pre-made Cynomolgus/Rhesus macaque MST1R siRNA oligo Duplex | 704437 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089993 | Pre-made Cat/Feline MST1R/RON/MST1R siRNA oligo Duplex | 101089993 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo444854 | Pre-made Dog/Canine MST1R siRNA oligo Duplex | 444854 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525504 | Pre-made Bovines/Cattle MST1R siRNA oligo Duplex | 525504 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062492 | Pre-made Equine/Horse MST1R siRNA oligo Duplex | 100062492 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MST1R/RON/CD136 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T01973-Ab | Human | Anti-Human MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T01973-Ab | Rat | Anti-Rat MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T01973-Ab | Mouse | Anti-Mouse MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T01973-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T01973-Ab | Cat/Feline | Anti-Cat/Feline MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T01973-Ab | Dog/Canine | Anti-Dog/Canine MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T01973-Ab | Bovines/Cattle | Anti-Bovines/Cattle MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T01973-Ab | Equine/Horse | Anti-Equine/Horse MST1R/RON/CD136 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MST1R/RON/CD136 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T01973-Ag | Human | Human MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T01973-Ag | Rat | Rat MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T01973-Ag | Mouse | Mouse MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T01973-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T01973-Ag | Cat/Feline | Cat/Feline MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T01973-Ag | Dog/Canine | Dog/Canine MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T01973-Ag | Bovines/Cattle | Bovines/Cattle MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T01973-Ag | Equine/Horse | Equine/Horse MST1R/RON/CD136 VLP (virus-like particle) | HEK293 | Products Developing |
