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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
| Target ID |
GM-T01908
|
| Target Name |
Kallikrein 2/KLK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3817
|
| Gene ID |
3817 (Homo sapiens)
|
| Target Alternative Names |
Glandular kallikrein-1 (hGK-1),KLK2,KLK2A2,Kallikrein 2,Kallikrein-2,Tissue kallikrein-2,hGK-1,hK2
|
| Uniprot Accession |
P20151
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
Renin-angiotensin system
|
| Gene Ensembl |
ENSG00000167751
|
Kallikrein 2/KLK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3817 | Pre-made Human KLK2/hK2/hGK-1 siRNA oligo Duplex | 3817 | Human | In-vitro grade; in-vivo grade | Detail |
Kallikrein 2/KLK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T01908-Ab | Human | Anti-Human Kallikrein 2/KLK2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Kallikrein 2/KLK2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T01908-Ag | Human | Human Kallikrein 2/KLK2 recombinant protein | Mammalian cell | Detail |
