Explore CD29/Integrin Beta 1/Integrin beta 1/ITGB1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T01851
|
| Target Name |
CD29/Integrin Beta 1/Integrin beta 1/ITGB1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3688
|
| Gene ID |
100055024 (Equus caballus), 16412 (Mus musculus), 24511 (Rattus norvegicus), 281876 (Bos taurus) 3688 (Homo sapiens), 477956 (Canis lupus familiaris), 574312 (Macaca mulatta), 751821 (Felis catus)
|
| Target Alternative Names |
4633401G24Rik,CD29,FNRB,Fibronectin receptor subunit beta,Fnrb,GPIIA,Glycoprotein IIa (GPIIA),Gm9863,ITGB1,Integrin Beta 1,Integrin beta 1,Integrin beta-1,Itgb1,MDF2,MSK12,VLA-4 subunit beta,VLA-BETA,VLAB,gpIIa
|
| Uniprot Accession |
P09055,P49134,P53712,P05556,P53713
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer, Breast Cancer, Malignant neoplasm of prostate
|
| Disease from KEGG |
Rap1 signaling pathway, Phagosome, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Tight junction, Platelet activation, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pertussis, Yersinia infection, Leishmaniasis, Toxoplasmosis, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000022498, ENSMUSG00000025809, ENSBTAG00000015910, ENSG00000150093, ENSCAFG00845002947, ENSMMUG00000017767
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD29/Integrin Beta 1/Integrin beta 1/ITGB1 cDNA Clones/ORF Plasmid
CD29/Integrin Beta 1/Integrin beta 1/ITGB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3688 | Pre-made Human ITGB1/CD29/FNRB siRNA oligo Duplex | 3688 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24511 | Pre-made Rat Itgb1 siRNA oligo Duplex | 24511 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16412 | Pre-made Mouse Itgb1/CD29/Fnrb siRNA oligo Duplex | 16412 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574312 | Pre-made Cynomolgus/Rhesus macaque ITGB1 siRNA oligo Duplex | 574312 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo751821 | Pre-made Cat/Feline ITGB1/CD29 siRNA oligo Duplex | 751821 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477956 | Pre-made Dog/Canine ITGB1 siRNA oligo Duplex | 477956 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281876 | Pre-made Bovines/Cattle ITGB1 siRNA oligo Duplex | 281876 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055024 | Pre-made Equine/Horse ITGB1/CD29 siRNA oligo Duplex | 100055024 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD29/Integrin Beta 1/Integrin beta 1/ITGB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T01851-Ab | Human | Anti-Human CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T01851-Ab | Rat | Anti-Rat CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T01851-Ab | Mouse | Anti-Mouse CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T01851-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T01851-Ab | Cat/Feline | Anti-Cat/Feline CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T01851-Ab | Dog/Canine | Anti-Dog/Canine CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T01851-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T01851-Ab | Equine/Horse | Anti-Equine/Horse CD29/Integrin Beta 1/Integrin beta 1/ITGB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T01851-Ag | Human | Human CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T01851-Ag | Rat | Rat CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T01851-Ag | Mouse | Mouse CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T01851-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T01851-Ag | Cat/Feline | Cat/Feline CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T01851-Ag | Dog/Canine | Dog/Canine CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T01851-Ag | Bovines/Cattle | Bovines/Cattle CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T01851-Ag | Equine/Horse | Equine/Horse CD29/Integrin Beta 1/Integrin beta 1/ITGB1 VLP (virus-like particle) | HEK293 | Products Developing |