ADRA2C Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore ADRA2C gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]

Target ID GM-T01777
Target Name ADRA2C
Gene Group ldentifer
(Target Gene ID in Homo species)
152
Gene ID 101087990 (Felis catus), 111772982 (Equus caballus), 11553 (Mus musculus), 152 (Homo sapiens)
24175 (Rattus norvegicus), 407139 (Bos taurus), 488793 (Canis lupus familiaris), 719763 (Macaca mulatta)
Target Alternative Names ADRA2C,ADRA2L2,ADRA2RL2,ADRARL2,ALPHA2CAR,Adra-2c,Adra2c,Alpha-2 adrenergic receptor subtype C4,Alpha-2C adrenergic receptor,Alpha-2C adrenoreceptor (Alpha-2C adrenoceptor,Alpha-2CAR),[a]2C,alpha2-C4,alpha2C
Uniprot Accession Q01337,P18825,P22086
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease from KEGG cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction
Gene Ensembl ENSMUSG00000045318, ENSG00000184160, ENSBTAG00000045994, ENSCAFG00845010654, ENSMMUG00000014781
Target Classification GPCR


Pre-made viral vector of ADRA2C cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLPm005297Mouse Adra2c/Adra-2c/alpha2-C4 Lentivirus plasmidNM_007418.311553MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm005297Mouse Adra2c/Adra-2c/alpha2-C4 Lentivirus particleNM_007418.311553MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


ADRA2C siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo152Pre-made Human ADRA2C/ADRA2L2/ADRARL2 siRNA oligo Duplex152HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24175Pre-made Rat Adra2c siRNA oligo Duplex24175RatIn-vitro grade; in-vivo gradeDetail
pGMoligo11553Pre-made Mouse Adra2c/[a]2C/Adra-2c siRNA oligo Duplex11553MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo719763Pre-made Cynomolgus/Rhesus macaque ADRA2C siRNA oligo Duplex719763Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101087990Pre-made Cat/Feline ADRA2C siRNA oligo Duplex101087990Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo488793Pre-made Dog/Canine ADRA2C siRNA oligo Duplex488793Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo407139Pre-made Bovines/Cattle ADRA2C siRNA oligo Duplex407139Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo111772982Pre-made Equine/Horse ADRA2C siRNA oligo Duplex111772982Equine/HorseIn-vitro grade; in-vivo gradeDetail


ADRA2C antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T01777-AbHumanAnti-Human ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T01777-AbRatAnti-Rat ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T01777-AbMouseAnti-Mouse ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T01777-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T01777-AbCat/FelineAnti-Cat/Feline ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T01777-AbDog/CanineAnti-Dog/Canine ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T01777-AbBovines/CattleAnti-Bovines/Cattle ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T01777-AbEquine/HorseAnti-Equine/Horse ADRA2C monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


ADRA2C VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T01777-AgHumanHuman ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T01777-AgRatRat ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T01777-AgMouseMouse ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T01777-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T01777-AgCat/FelineCat/Feline ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T01777-AgDog/CanineDog/Canine ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T01777-AgBovines/CattleBovines/Cattle ADRA2C VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T01777-AgEquine/HorseEquine/Horse ADRA2C VLP (virus-like particle)HEK293Products Developing