Explore TSG101 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T01283
|
| Target Name |
TSG101
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7251
|
| Gene ID |
100057099 (Equus caballus), 101100915 (Felis catus), 22088 (Mus musculus), 292925 (Rattus norvegicus)
485406 (Canis lupus familiaris), 507659 (Bos taurus), 693787 (Macaca mulatta), 7251 (Homo sapiens)
|
| Target Alternative Names |
CC2,ESCRT-I complex subunit TSG101,Rw,TSG10,TSG101,Tsg101,Tumor susceptibility gene 101 protein,VPS23
|
| Uniprot Accession |
Q61187,Q6IRE4,Q99816
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000004362, ENSMUSG00000014402, ENSCAFG00845016679, ENSBTAG00000013563, ENSMMUG00000014613, ENSG00000074319
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of TSG101 cDNA Clones/ORF Plasmid
TSG101 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7251 | Pre-made Human TSG101/TSG10/VPS23 siRNA oligo Duplex | 7251 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292925 | Pre-made Rat Tsg101/Rw siRNA oligo Duplex | 292925 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22088 | Pre-made Mouse Tsg101/CC2 siRNA oligo Duplex | 22088 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693787 | Pre-made Cynomolgus/Rhesus macaque TSG101 siRNA oligo Duplex | 693787 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100915 | Pre-made Cat/Feline TSG101 siRNA oligo Duplex | 101100915 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485406 | Pre-made Dog/Canine TSG101 siRNA oligo Duplex | 485406 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507659 | Pre-made Bovines/Cattle TSG101 siRNA oligo Duplex | 507659 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057099 | Pre-made Equine/Horse TSG101 siRNA oligo Duplex | 100057099 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TSG101 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T01283-Ab | Human | Anti-Human TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T01283-Ab | Rat | Anti-Rat TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T01283-Ab | Mouse | Anti-Mouse TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T01283-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T01283-Ab | Cat/Feline | Anti-Cat/Feline TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T01283-Ab | Dog/Canine | Anti-Dog/Canine TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T01283-Ab | Bovines/Cattle | Anti-Bovines/Cattle TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T01283-Ab | Equine/Horse | Anti-Equine/Horse TSG101 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TSG101 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T01283-Ag | Human | Human TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T01283-Ag | Rat | Rat TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T01283-Ag | Mouse | Mouse TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T01283-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T01283-Ag | Cat/Feline | Cat/Feline TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T01283-Ag | Dog/Canine | Dog/Canine TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T01283-Ag | Bovines/Cattle | Bovines/Cattle TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T01283-Ag | Equine/Horse | Equine/Horse TSG101 VLP (virus-like particle) | HEK293 | Products Developing |
