Explore ABCA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
| Target ID |
GM-T00494
|
| Target Name |
ABCA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
19
|
| Gene ID |
100054241 (Equus caballus), 101083885 (Felis catus), 11303 (Mus musculus), 19 (Homo sapiens)
313210 (Rattus norvegicus), 481651 (Canis lupus familiaris), 535379 (Bos taurus), 716146 (Macaca mulatta)
|
| Target Alternative Names |
ABC-1,ABC1,ABCA1,ATP-binding cassette 1),ATP-binding cassette sub-family A member 1,ATP-binding cassette transporter 1 (ABC-1,Abc1,Abca1,CERP,Cholesterol efflux regulatory protein,HDLCQTL13,HDLDT1,HPALP1,Phospholipid-transporting ATPase ABCA1,TGD
|
| Uniprot Accession |
P41233,O95477
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
ABC transporters, Fat digestion and absorption, Cholesterol metabolism, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000008852, ENSMUSG00000015243, ENSG00000165029, ENSCAFG00845010374, ENSBTAG00000020661, ENSMMUG00000020608
|
| Target Classification |
Tumor-associated antigen (TAA)
|
ABCA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo19 | Pre-made Human ABCA1/TGD/ABC1 siRNA oligo Duplex | 19 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313210 | Pre-made Rat Abca1 siRNA oligo Duplex | 313210 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11303 | Pre-made Mouse Abca1/Abc1/ABC-1 siRNA oligo Duplex | 11303 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716146 | Pre-made Cynomolgus/Rhesus macaque ABCA1 siRNA oligo Duplex | 716146 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083885 | Pre-made Cat/Feline ABCA1 siRNA oligo Duplex | 101083885 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481651 | Pre-made Dog/Canine ABCA1 siRNA oligo Duplex | 481651 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535379 | Pre-made Bovines/Cattle ABCA1/ABC-1 siRNA oligo Duplex | 535379 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054241 | Pre-made Equine/Horse ABCA1 siRNA oligo Duplex | 100054241 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ABCA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T00494-Ab | Human | Anti-Human ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T00494-Ab | Rat | Anti-Rat ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T00494-Ab | Mouse | Anti-Mouse ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T00494-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T00494-Ab | Cat/Feline | Anti-Cat/Feline ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T00494-Ab | Dog/Canine | Anti-Dog/Canine ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T00494-Ab | Bovines/Cattle | Anti-Bovines/Cattle ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T00494-Ab | Equine/Horse | Anti-Equine/Horse ABCA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ABCA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T00494-Ag | Human | Human ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T00494-Ag | Rat | Rat ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T00494-Ag | Mouse | Mouse ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T00494-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T00494-Ag | Cat/Feline | Cat/Feline ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T00494-Ag | Dog/Canine | Dog/Canine ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T00494-Ag | Bovines/Cattle | Bovines/Cattle ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T00494-Ag | Equine/Horse | Equine/Horse ABCA1 VLP (virus-like particle) | HEK293 | Products Developing |
