Explore IL-23R/IL23R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
| Target ID |
GM-T00484
|
| Target Name |
IL-23R/IL23R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
149233
|
| Gene ID |
100053807 (Equus caballus), 101087763 (Felis catus), 149233 (Homo sapiens), 209590 (Mus musculus) 609732 (Canis lupus familiaris), 614367 (Bos taurus), 689932 (Rattus norvegicus), 700440 (Macaca mulatta)
|
| Target Alternative Names |
IL-23 receptor,IL-23R,IL23R,Il23r,Interleukin-23 receptor,PSORS7
|
| Uniprot Accession |
Q5VWK5,Q8K4B4
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Th17 cell differentiation, Pathways in cancer, Inflammatory bowel disease
|
| Gene Ensembl |
ENSECAG00000017239, ENSG00000162594, ENSMUSG00000049093, ENSCAFG00845027041, ENSBTAG00000014983, ENSMMUG00000000648
|
| Target Classification |
Cytokine Receptor
|
Pre-made viral vector of IL-23R/IL23R cDNA Clones/ORF Plasmid
IL-23R/IL23R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo149233 | Pre-made Human IL23R/PSORS7 siRNA oligo Duplex | 149233 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo689932 | Pre-made Rat Il23r siRNA oligo Duplex | 689932 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo209590 | Pre-made Mouse Il23r/IL-23R siRNA oligo Duplex | 209590 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700440 | Pre-made Cynomolgus/Rhesus macaque IL23R siRNA oligo Duplex | 700440 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087763 | Pre-made Cat/Feline IL23R siRNA oligo Duplex | 101087763 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609732 | Pre-made Dog/Canine IL23R siRNA oligo Duplex | 609732 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614367 | Pre-made Bovines/Cattle IL23R/IL-23R siRNA oligo Duplex | 614367 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053807 | Pre-made Equine/Horse IL23R siRNA oligo Duplex | 100053807 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-23R/IL23R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T00484-Ab | Human | Anti-Human IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T00484-Ab | Rat | Anti-Rat IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T00484-Ab | Mouse | Anti-Mouse IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T00484-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T00484-Ab | Cat/Feline | Anti-Cat/Feline IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T00484-Ab | Dog/Canine | Anti-Dog/Canine IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T00484-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T00484-Ab | Equine/Horse | Anti-Equine/Horse IL-23R/IL23R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-23R/IL23R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T00484-Ag | Human | Human IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T00484-Ag | Rat | Rat IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T00484-Ag | Mouse | Mouse IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T00484-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T00484-Ag | Cat/Feline | Cat/Feline IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T00484-Ag | Dog/Canine | Dog/Canine IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T00484-Ag | Bovines/Cattle | Bovines/Cattle IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T00484-Ag | Equine/Horse | Equine/Horse IL-23R/IL23R VLP (virus-like particle) | HEK293 | Products Developing |