Explore SECISBP2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
| Target ID |
GM-SE1640
|
| Target Name |
SECISBP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
79048
|
| Gene ID |
100062130 (Equus caballus), 101096115 (Felis catus), 476351 (Canis lupus familiaris), 511202 (Bos taurus) 697442 (Macaca mulatta), 75420 (Mus musculus), 79048 (Homo sapiens), 79049 (Rattus norvegicus)
|
| Target Alternative Names |
2210413N07Rik,2810012K13Rik,SBP2,SECIS-binding protein 2,SECISBP2,Sbp2,Secisbp2,Selenocysteine insertion sequence-binding protein 2,THMA1
|
| Uniprot Accession |
Q3U1C4,Q96T21,Q9QX72
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSECAG00000015868, ENSCAFG00845019299, ENSBTAG00000001939, ENSMMUG00000012532, ENSMUSG00000035139, ENSG00000187742
|
SECISBP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79048 | Pre-made Human SECISBP2/SBP2/THMA1 siRNA oligo Duplex | 79048 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79049 | Pre-made Rat Secisbp2/Sbp2 siRNA oligo Duplex | 79049 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo75420 | Pre-made Mouse Secisbp2/SBP2/2210413N07Rik siRNA oligo Duplex | 75420 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697442 | Pre-made Cynomolgus/Rhesus macaque SECISBP2 siRNA oligo Duplex | 697442 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096115 | Pre-made Cat/Feline SECISBP2 siRNA oligo Duplex | 101096115 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476351 | Pre-made Dog/Canine SECISBP2 siRNA oligo Duplex | 476351 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511202 | Pre-made Bovines/Cattle SECISBP2 siRNA oligo Duplex | 511202 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062130 | Pre-made Equine/Horse SECISBP2 siRNA oligo Duplex | 100062130 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SECISBP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1640-Ab | Human | Anti-Human SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1640-Ab | Rat | Anti-Rat SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1640-Ab | Mouse | Anti-Mouse SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1640-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1640-Ab | Cat/Feline | Anti-Cat/Feline SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1640-Ab | Dog/Canine | Anti-Dog/Canine SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1640-Ab | Bovines/Cattle | Anti-Bovines/Cattle SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1640-Ab | Equine/Horse | Anti-Equine/Horse SECISBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SECISBP2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1640-Ag | Human | Human SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1640-Ag | Rat | Rat SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1640-Ag | Mouse | Mouse SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1640-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1640-Ag | Cat/Feline | Cat/Feline SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1640-Ag | Dog/Canine | Dog/Canine SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1640-Ag | Bovines/Cattle | Bovines/Cattle SECISBP2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1640-Ag | Equine/Horse | Equine/Horse SECISBP2 recombinant protein | Mammalian cell | Detail |