Explore OAS1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, May 2022]
| Target ID |
GM-SE1429
|
| Target Name |
OAS1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4938
|
| Gene ID |
100034147 (Equus caballus), 101087875 (Felis catus), 4938 (Homo sapiens), 608778 (Canis lupus familiaris) 712265 (Macaca mulatta)
|
| Target Alternative Names |
(2-5')oligo(A) synthase 1,2'-5'-oligoadenylate synthase 1,2-5A synthase 1,E18/E16,IFI-4,IMD100,OAS1,OIAS,OIASI,p46/p42 OAS
|
| Uniprot Accession |
P00973
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
NOD-like receptor signaling pathway, Hepatitis C, Measles, Influenza A, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000013435, ENSG00000089127, ENSCAFG00845021979, ENSMMUG00000012782
|
Pre-made viral vector of OAS1 cDNA Clones/ORF Plasmid
OAS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4938 | Pre-made Human OAS1/OIAS/IFI-4 siRNA oligo Duplex | 4938 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712265 | Pre-made Cynomolgus/Rhesus macaque OAS1 siRNA oligo Duplex | 712265 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087875 | Pre-made Cat/Feline OAS1 siRNA oligo Duplex | 101087875 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608778 | Pre-made Dog/Canine OAS1 siRNA oligo Duplex | 608778 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034147 | Pre-made Equine/Horse OAS1 siRNA oligo Duplex | 100034147 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OAS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1429-Ab | Human | Anti-Human OAS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1429-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OAS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1429-Ab | Cat/Feline | Anti-Cat/Feline OAS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1429-Ab | Dog/Canine | Anti-Dog/Canine OAS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1429-Ab | Equine/Horse | Anti-Equine/Horse OAS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
OAS1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1429-Ag | Human | Human OAS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1429-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OAS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1429-Ag | Cat/Feline | Cat/Feline OAS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1429-Ag | Dog/Canine | Dog/Canine OAS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1429-Ag | Equine/Horse | Equine/Horse OAS1 recombinant protein | Mammalian cell | Detail |