Explore C1r/C1R gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]
Target ID |
GM-SE1392
|
Target Name |
C1r/C1R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
715
|
Gene ID |
100060297 (Equus caballus), 101088940 (Felis catus), 312705 (Rattus norvegicus), 477707 (Canis lupus familiaris) 511581 (Bos taurus), 715 (Homo sapiens)
|
Target Alternative Names |
C1R,C1r,Complement C1r subcomponent,Complement component 1 subcomponent r,EDS8,EDSPD1
|
Uniprot Accession |
P00736
|
Uniprot Entry Name |
|
Protein Sub-location |
Secreted Protein/Potential Cytokines
|
Category |
|
Disease |
|
Disease from KEGG |
Phagosome, Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection
|
Gene Ensembl |
ENSECAG00000021429, ENSCAFG00845025120, ENSBTAG00000008612, ENSG00000159403
|
Target Classification |
|
Pre-made viral vector of C1r/C1R cDNA Clones/ORF Plasmid
C1r/C1R siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo715 | Pre-made Human C1R/EDS8/EDSPD1 siRNA oligo Duplex | 715 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo312705 | Pre-made Rat C1r siRNA oligo Duplex | 312705 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo101088940 | Pre-made Cat/Feline C1R siRNA oligo Duplex | 101088940 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo477707 | Pre-made Dog/Canine C1R siRNA oligo Duplex | 477707 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo511581 | Pre-made Bovines/Cattle C1R siRNA oligo Duplex | 511581 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100060297 | Pre-made Equine/Horse C1R siRNA oligo Duplex | 100060297 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
C1r/C1R antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-SE1392-Ab | Human | Anti-Human C1r/C1R monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-rg-SE1392-Ab | Rat | Anti-Rat C1r/C1R monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-felg-SE1392-Ab | Cat/Feline | Anti-Cat/Feline C1r/C1R monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cang-SE1392-Ab | Dog/Canine | Anti-Dog/Canine C1r/C1R monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-bovg-SE1392-Ab | Bovines/Cattle | Anti-Bovines/Cattle C1r/C1R monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-equg-SE1392-Ab | Equine/Horse | Anti-Equine/Horse C1r/C1R monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
C1r/C1R recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-SE1392-Ag | Human | Human C1r/C1R recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-SE1392-Ag | Rat | Rat C1r/C1R recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-SE1392-Ag | Cat/Feline | Cat/Feline C1r/C1R recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-SE1392-Ag | Dog/Canine | Dog/Canine C1r/C1R recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-SE1392-Ag | Bovines/Cattle | Bovines/Cattle C1r/C1R recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-SE1392-Ag | Equine/Horse | Equine/Horse C1r/C1R recombinant protein | Mammalian cell | Detail |