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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010]
| Target ID |
GM-SE1343
|
| Target Name |
TSG-6/TNFAIP6
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7130
|
| Gene ID |
100034068 (Equus caballus), 101100655 (Felis catus), 21930 (Mus musculus), 476147 (Canis lupus familiaris) 493710 (Bos taurus), 694699 (Macaca mulatta), 7130 (Homo sapiens), 84397 (Rattus norvegicus)
|
| Target Alternative Names |
Hyaluronate-binding protein,TNF-stimulated gene 6 protein (TSG-6),TNFAIP6,TSG-6,TSG6,Tnfaip6,Tnfip6,Tsg6,Tumor necrosis factor alpha-induced protein 6 (TNF alpha-induced protein 6),Tumor necrosis factor-inducible gene 6 protein,tsg-6
|
| Uniprot Accession |
O08859,P98066
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Ovary Cancer
|
| Gene Ensembl |
ENSECAG00000012104, ENSMUSG00000053475, ENSCAFG00845008460, ENSBTAG00000007239, ENSMMUG00000010927, ENSG00000123610
|
Pre-made viral vector of TSG-6/TNFAIP6 cDNA Clones/ORF Plasmid
TSG-6/TNFAIP6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7130 | Pre-made Human TNFAIP6/TSG6/TSG-6 siRNA oligo Duplex | 7130 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84397 | Pre-made Rat Tnfaip6/Tnfip6 siRNA oligo Duplex | 84397 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21930 | Pre-made Mouse Tnfaip6/Tsg6/TSG-6 siRNA oligo Duplex | 21930 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694699 | Pre-made Cynomolgus/Rhesus macaque TNFAIP6 siRNA oligo Duplex | 694699 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100655 | Pre-made Cat/Feline TNFAIP6 siRNA oligo Duplex | 101100655 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476147 | Pre-made Dog/Canine TNFAIP6 siRNA oligo Duplex | 476147 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493710 | Pre-made Bovines/Cattle TNFAIP6/tsg-6 siRNA oligo Duplex | 493710 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034068 | Pre-made Equine/Horse TNFAIP6/TSG-6 siRNA oligo Duplex | 100034068 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TSG-6/TNFAIP6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1343-Ab | Human | Anti-Human TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE1343-Ab | Rat | Anti-Rat TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE1343-Ab | Mouse | Anti-Mouse TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1343-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE1343-Ab | Cat/Feline | Anti-Cat/Feline TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE1343-Ab | Dog/Canine | Anti-Dog/Canine TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE1343-Ab | Bovines/Cattle | Anti-Bovines/Cattle TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE1343-Ab | Equine/Horse | Anti-Equine/Horse TSG-6/TNFAIP6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
TSG-6/TNFAIP6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1343-Ag | Human | Human TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1343-Ag | Rat | Rat TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1343-Ag | Mouse | Mouse TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1343-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1343-Ag | Cat/Feline | Cat/Feline TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1343-Ag | Dog/Canine | Dog/Canine TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1343-Ag | Bovines/Cattle | Bovines/Cattle TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1343-Ag | Equine/Horse | Equine/Horse TSG-6/TNFAIP6 recombinant protein | Mammalian cell | Detail |